| Pos. | Starters | Team | Points | PPG | Total | Games | Breakdown |
| C | J.T. Realmuto | Phi | 27 | 3.09 | 392 | 7 | 16 TB, 7 RBI, 3 Runs, 1 SB |
| 1B | Bobby Bradley | Cle | 15 | 2.89 | 202 | 7 | 9 TB, 3 RBI, 2 Runs, 1 BB |
| 2B (OF) | Brandon Lowe | TB | 17 | 3.51 | 505 | 5 | 10 TB, 3 RBI, 2 Runs, 2 BB |
| SS (2B) | Marcus Semien | Tex | 27 | 4.04 | 630 | 7 | 17 TB, 4 RBI, 4 Runs, 2 BB |
| 3B | Manny Machado | SD | 31 | 3.60 | 529 | 6 | 16 TB, 8 RBI, 4 Runs, 3 BB |
| OF | Robbie Grossman | Det | 14 | 3.26 | 486 | 5 | 4 TB, 4 Runs, 1 SB, 5 BB |
| OF (DH) | Austin Meadows | TB | 17 | 3.42 | 472 | 4 | 8 TB, 3 RBI, 4 Runs, 2 BB |
| OF | Bryan Reynolds | Pit | 17 | 3.45 | 524 | 6 | 7 TB, 2 RBI, 3 Runs, 5 BB |
| DH (OF) | George Springer | Tor | 23 | 3.75 | 270 | 7 | 13 TB, 3 RBI, 4 Runs, 3 BB |
| Pos. | 1st Backup | Team | Points | PPG | Total | Games | Breakdown |
| C | Mitch Garver | Tex | 0(15) | 3.02 | 196 | 4 | 9 TB, 3 RBI, 2 Runs, 1 BB |
| 1B (3B,OF) | Patrick Wisdom | ChN | 0(14) | 3.08 | 326 | 5 | 5 TB, 4 RBI, 1 Run, 1 SB, 3 BB |
| 2B | Cesar Hernández | Was | 2(8) | 2.83 | 411 | 6 | 4 TB, 2 Runs, 2 BB |
| SS | Miguel Rojas | Mia | 0(14) | 2.76 | 351 | 5 | 8 TB, 2 RBI, 1 Run, 1 SB, 2 BB |
| 3B (1B,2B) | Eduardo Escobar | NYN | 1(11) | 3.24 | 453 | 7 | 4 TB, 4 RBI, 1 Run, 2 BB |
| OF | Austin Hays | Bal | 19(23) | 3.15 | 391 | 7 | 13 TB, 3 RBI, 4 Runs, 3 BB |
| DH (OF) | Akil Baddoo | Det | 0(8) | 3.01 | 334 | 4 | 4 TB, 2 RBI, 1 Run, 1 BB |
| Pos. | 2nd Backup | Team | Points | PPG | Total | Games | Breakdown |
| 1B | Jesus Aguilar | Mia | DNP | 2.99 | 392 | 0 | Did Not Play |
| 3B (SS) | Giovanny Urshela | Min | 0(12) | 2.45 | 270 | 6 | 7 TB, 4 Runs, 1 BB |
| DH (1B,2B,SS) | Jake Cronenworth | SD | 0(17) | 3.23 | 472 | 6 | 10 TB, 3 RBI, 2 Runs, 2 BB |
| Pos. | 3rd Backup | Team | Points | PPG | Total | Games | Breakdown |
| OF | Wil Myers | SD | 0(5) | 2.57 | 363 | 5 | 3 TB, 2 Runs |
| Pitching Staff Alignment | |||||||
| 10 Starts, 0 Relievers | |||||||
| Pos. | Pitching Order | Team | Points | PPG | Total | Games | Breakdown |
| 1st SP | Lance Lynn | ChA | 0 | 13.96 | 377 | 1 | Played, No Points Earned |
| 2nd SP | Brandon Woodruff | Mil | 15 | 14.03 | 407 | 1 | 15 Non W/S+ |
| 3rd SP (RP) | Cal Quantrill | Cle | 20 | 8.51 | 332 | 1 | 1 Win, 10 W/S+ |
| 4th SP | Lance McCullers | Hou | 9 | 13.52 | 365 | 1 | 9 Non W/S+ |
| 5th SP | Anthony DeSclafani | SF | 6 | 12.90 | 387 | 1 | 6 Non W/S+ |
| 6th SP | Max Fried | Atl | 33 | 14.78 | 399 | 1 | 1 Win, 1 CG, 18 W/S+ |
| 7th SP | Marco Gonzales | Sea | 40 | 12.83 | 308 | 2 | 2 Wins, 20 W/S+ |
| 8th SP | Sean Manaea | Oak | 21 | 11.94 | 370 | 2 | 21 Non W/S+ |
| 9th SP | Taijuan Walker | NYN | 0(0) | 9.66 | 280 | 1 | Played, No Points Earned |
| 10th SP | Tarik Skubal | Det | 0(12) | 9.60 | 288 | 1 | 12 Non W/S+ |
| 1st RP | Liam Hendriks | ChA | 0(30) | 8.36 | 552 | 4 | 2 Saves, 4 W/S+, 6 Non W/S+ |
| Hit=210 Pit=144 Total=354 | |||||||
| Pos. | Injured List | Team | Points | PPG | Total | Games | Breakdown |
| SP | Chris Bassitt | NYN | 0(30)(9) | 14.04 | 365 | 1 | 9 Non W/S+ |
| SP | Dakota Hudson | StL | 0(30)(12) | 12.00 | 12 | 1 | 1 Win, 2 W/S+ |
| OF | Marcell Ozuna | Atl | DNP | 2.77 | 133 | 0 | Did Not Play |