| Round | Overall | Player |
|---|---|---|
| 1 | 2nd | DH Shohei Ohtani LAA |
| 2 | 23rd | 2B Marcus Semien Tex |
| 3 | 26th | SP Julio Urías LAD |
| 4 | 47th | 3B Alex Bregman Hou |
| 5 | 50th | SS Francisco Lindor NYN |
| 6 | 71st | RP Raisel Iglesias Atl |
| 7 | 74th | SP Chris Bassitt Tor |
| 8 | 95th | 1B Joshua Bell Cle |
| 9 | 98th | OF Hunter Renfroe Mil |
| 10 | 119th | OF Mitch Haniger SF |
| 11 | 122nd | SP Ian Anderson Atl |
| 12 | 143rd | C Willson Contreras StL |
| 13 | 146th | SP Anthony DeSclafani SF |
| 14 | 167th | OF Adam Duvall Atl |
| 15 | 170th | 1B C.J. Cron Col |
| 16 | 191st | 1B Luke Voit SD |
| 17 | 194th | OF Randal Grichuk Col |
| 18 | 215th | SS Brandon Crawford SF |
| 19 | 218th | 3B Eugenio Suarez Sea |
| 20 | 239th | SP Tanner Houck Bos |
| 21 | 242nd | C Mike Zunino Cle |
| 22 | 263rd | OF Anthony Santander Bal |
| 23 | 266th | SP Dylan Bundy Min |
| 24 | 287th | SP Elieser Hernandez Mia |
| 25 | 290th | 2B Cesar Hernández Was |
| 26 | 311th | RP Ryan Tepera ChA |
| 27 | 314th | SP Steven Matz StL |
| 28 | 335th | SP Dane Dunning Tex |
| 29 | 338th | OF David Peralta TB |