| Round | Overall | Player |
|---|---|---|
| 1 | 4th | OF Juan Soto SD |
| 2 | 21st | SS Xander Bogaerts SD |
| 3 | 28th | 3B Kris Bryant Col |
| 4 | 45th | RP Liam Hendriks ChA |
| 5 | 52nd | 1B Max Muncy LAD |
| 5 | 52nd | SS Max Muncy Oak |
| 6 | 69th | RP Emmanuel Clase Cle |
| 7 | 76th | SS Carlos Correa SF |
| 8 | 93rd | C Will Smith LAD |
| 9 | 100th | 2B Whit Merrifield Tor |
| 10 | 117th | OF Bryan Reynolds Pit |
| 11 | 124th | OF Marcell Ozuna Atl |
| 12 | 141st | RP Scott Barlow KC |
| 13 | 148th | SS Dansby Swanson Atl |
| 14 | 165th | SP Hyun-Jin Ryu Tor |
| 15 | 172nd | SP Chris Flexen Sea |
| 16 | 189th | SP Kyle Hendricks ChN |
| 17 | 196th | SP Sonny Gray Min |
| 18 | 213th | RP Lou Trivino NYA |
| 19 | 220th | 1B Carlos Santana KC |
| 20 | 237th | OF Alex Verdugo Bos |
| 21 | 244th | SP Kyle Gibson Phi |
| 22 | 261st | C Christian Vazquez Bos |
| 23 | 268th | SP Corey Kluber TB |
| 24 | 285th | OF Mark Canha NYN |
| 25 | 292nd | SP Merrill Kelly Ari |
| 26 | 309th | 1B Jonathan Schoop Det |
| 27 | 316th | SP Wade Miley ChN |
| 28 | 333rd | C Yan Gomes ChN |
| 29 | 340th | OF Hunter Dozier KC |