| Quarterback | ||||
|---|---|---|---|---|
| Player | Games | Points | PPG | Stats |
| Matthew Stafford | 15 | 291 | 19.41 | 3965 Pass , 65 Rush , 24 TD , 11 Int 2 2-Pt |
| Jimmy Garoppolo | 6 | 78 | 13.02 | 1205 Pass , 39 Rush , 7 TD , 9 Int 1 2-Pt |
| Running Back | ||||
| Player | Games | Points | PPG | Stats |
| Kyren Williams | 12 | 241 | 20.08 | 1144 Rush , 206 Receiving , 32 Rec , 15 TD , 1 2-Pt, 2 Fumb |
| Royce Freeman | 8 | 46 | 5.71 | 319 Rush , 13 Receiving , 1 Rec , 2 TD |
| Ronnie Rivers | 7 | 18 | 2.51 | 129 Rush , 22 Receiving , 5 Rec |
| Zach Evans | 3 | 2 | 0.63 | 19 Rush |
| Wide Receiver | ||||
| Player | Games | Points | PPG | Stats |
| Puka Nacua | 17 | 246 | 14.47 | 89 Rush , 1486 Receiving , 105 Rec , 6 TD |
| Cooper Kupp | 12 | 135 | 11.24 | -3 Rush , 737 Receiving , 59 Rec , 5 TD , 1 2-Pt |
| Tutu Atwell | 13 | 91 | 6.99 | 31 Rush , 483 Receiving , 39 Rec , 3 TD , 1 2-Pt |
| Demarcus Robinson | 8 | 75 | 9.43 | 23 Rush , 371 Receiving , 26 Rec , 4 TD , 1 Fumb |
| Ben Skowronek | 6 | 18 | 2.95 | 11 Rush , 66 Receiving , 8 Rec , 1 TD |
| Austin Trammell | 2 | 5 | 2.45 | 29 Receiving , 4 Rec |
| Tight End | ||||
| Player | Games | Points | PPG | Stats |
| Tyler Higbee | 14 | 85 | 6.07 | 495 Receiving , 47 Rec , 2 TD |
| Colby Parkinson | 13 | 49 | 3.76 | 244 Receiving , 25 Rec , 2 TD |
| Davis Allen | 4 | 21 | 5.13 | 95 Receiving , 10 Rec , 1 TD |
| Brycen Hopkins | 4 | 10 | 2.58 | 78 Receiving , 5 Rec |
| Place Kicker | ||||
| Player | Games | Points | PPG | Stats |
| Lucas Havrisik | 5 | 42 | 8.40 | 6 FG(<40), 2 FG(40-49), 1 FG(50-59), 12 XP, 1 Miss(<40) |
| Defensive Line | ||||
| Player | Games | Points | PPG | Stats |
| Michael Hoecht | 16 | 110 | 6.88 | 45 Tackles, 36 Assists, 6.0 Sacks, 1 FF, 2 PD |
| Kobie Turner | 16 | 94 | 5.88 | 29 Tackles, 27 Assists, 9.0 Sacks, 2 PD |
| Jonah Williams | 16 | 57 | 3.56 | 20 Tackles, 28 Assists, 2.0 Sacks, 1 PD |
| Bobby Brown | 8 | 26 | 3.25 | 12 Tackles, 14 Assists |
| Desjuan Johnson | 5 | 20 | 4.00 | 6 Tackles, 3 Assists, 2.0 Sacks, 1 FF |
| Larrell Murchison | 10 | 16 | 1.60 | 7 Tackles, 9 Assists |
| Earnest Brown | 2 | 2 | 1.00 | 2 Assists |
| Linebacker | ||||
| Player | Games | Points | PPG | Stats |
| Ernest Jones | 15 | 169 | 11.27 | 75 Tackles, 70 Assists, 4.5 Sacks, 6 PD |
| Byron Young | 17 | 99 | 5.82 | 42 Tackles, 19 Assists, 8.0 Sacks, 2 FF |
| Christian Rozeboom | 17 | 89 | 5.24 | 48 Tackles, 32 Assists, 1 Int, 4 PD |
| Troy Reeder | 9 | 22 | 2.44 | 10 Tackles, 12 Assists |
| Jake Hummel | 8 | 10 | 1.25 | 7 Tackles, 3 Assists |
| Nick Hampton | 5 | 5 | 1.00 | 2 Tackles, 2 Assists, 1 PD |
| Ochaun Mathis | 2 | 2 | 1.00 | 1 Tackle, 1 Assist |
| Cornerback | ||||
| Player | Games | Points | PPG | Stats |
| Ahkello Witherspoon | 17 | 88 | 5.18 | 43 Tackles, 9 Assists, 3 Int, 2 Fum Rcvy, 15 PD |
| Derion Kendrick | 14 | 64 | 4.57 | 41 Tackles, 8 Assists, 1 Int, 10 PD |
| Decobie Durant | 13 | 45 | 3.46 | 23 Tackles, 16 Assists, 6 PD |
| Duke Shelley | 5 | 13 | 2.60 | 7 Tackles, 1 Assist, 1 Fum Rcvy, 2 PD |
| Tre'Vius Hodges-Tomlinson | 2 | 5 | 2.50 | 5 Tackles |
| Safety | ||||
| Player | Games | Points | PPG | Stats |
| Jordan Fuller | 17 | 126 | 7.41 | 61 Tackles, 33 Assists, 3 Int, 3 FF, 8 PD |
| Russ Yeast | 16 | 66 | 4.13 | 37 Tackles, 24 Assists, 5 PD |
| Quentin Lake | 14 | 62 | 4.43 | 42 Tackles, 11 Assists, 1 Fum Rcvy, 6 PD |
| John Johnson | 11 | 58 | 5.27 | 24 Tackles, 18 Assists, 2 Int, 6 PD |
| Jason Taylor | 1 | 1 | 1.00 | 1 Tackle |