*=Offensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 31.00 | Week 17, 2010 | SD | @Den@Den | 120 Rush, 19 Receiving, 3 TD |
| 2. | 27.00 | Week 10, 2016 | Phi | AtlAtl | 109 Rush, 30 Receiving, 2 TD, 1 2-Pt |
| 3. | 26.00 | Week 03, 2011 | SD | KCKC | 98 Rush, 51 Receiving, 2 TD |
| 4. | 22.00 | Week 15, 2011 | SD | BalBal | 90 Rush, 19 Receiving, 2 TD |
| 5. | 21.00 | Week 15, 2016 | Phi | @Bal@Bal | 128 Rush, 5 Receiving, 1 TD, 1 2-Pt |
| 6. | 19.00 | Week 14, 2013 | SD | NYGNYG | 103 Rush, 32 Receiving, 1 TD |
| 6. | 19.00 | Week 05, 2012 | SD | @NO@NO | 80 Rush, 59 Receiving, 1 TD |
| 8. | 18.00 | Week 07, 2015 | Phi | @Car@Car | 97 Rush, 24 Receiving, 1 TD |
| 8. | 18.00 | Week 15, 2013 | SD | @Den@Den | 127 Rush, 1 Receiving, 1 TD |
| 8. | 18.00 | Week 02, 2011 | SD | @NE@NE | 64 Rush, 62 Receiving, 1 TD |
| 11. | 17.00 | Week 03, 2015 | Phi | @NYJ@NYJ | 108 Rush, 20 Receiving, 1 TD, 1 Fumb |
| 11. | 17.00 | Week 12, 2014 | SD | StlStl | 105 Rush, 8 Receiving, 1 TD |
| 11. | 17.00 | Week 16, 2013 | SD | OakOak | 99 Rush, 20 Receiving, 1 TD |
| 11. | 17.00 | Week 07, 2013 | SD | @Jac@Jac | 110 Rush, 1 TD |
| 11. | 17.00 | Week 13, 2011 | SD | @Jac@Jac | 112 Rush, 2 Receiving, 1 TD |
| 16. | 15.00 | Week 02, 2016 | Phi | @Chi@Chi | 32 Rush, 3 Receiving, 2 TD |
| 16. | 15.00 | Week 05, 2015 | Phi | NONO | 73 Rush, 23 Receiving, 1 TD |
| 16. | 15.00 | Week 17, 2013 | SD | KCKC | 144 Rush, 11 Receiving |
| 19. | 14.00 | Week 11, 2013 | SD | @Mia@Mia | 127 Rush, 16 Receiving |
| 19. | 14.00 | Week 14, 2011 | SD | BufBuf | 114 Rush, 34 Receiving |
| 19. | 14.00 | Week 12, 2011 | SD | DenDen | 137 Rush, 5 Receiving |
| 19. | 14.00 | Week 04, 2011 | SD | MiaMia | 81 Rush, 68 Receiving |
| 19. | 14.00 | Week 16, 2010 | SD | @Cin@Cin | 55 Rush, 28 Receiving, 1 TD |
| 24. | 13.00 | Week 01, 2016 | Phi | CleCle | 77 Rush, 1 TD |
| 24. | 13.00 | Week 05, 2011 | SD | @Den@Den | 125 Rush, 7 Receiving |
| 24. | 13.00 | Week 14, 2010 | SD | KCKC | 65 Rush, 6 Receiving, 1 TD |
| 27. | 12.00 | Week 05, 2016 | Phi | @Det@Det | 42 Rush, 33 Receiving, 1 TD, 1 Fumb |
| 27. | 12.00 | Week 09, 2015 | Phi | @Dal@Dal | 67 Rush, 1 TD |
| 27. | 12.00 | Week 01, 2014 | SD | @ARI@ARI | 40 Rush, 20 Receiving, 1 TD |
| 27. | 12.00 | Week 12, 2013 | SD | @KC@KC | 55 Rush, 10 Receiving, 1 TD |
| 27. | 12.00 | Week 10, 2013 | SD | DenDen | 59 Rush, 2 Receiving, 1 TD |
| 27. | 12.00 | Week 04, 2010 | SD | AriAri | 55 Rush, 13 Receiving, 1 TD |
| 33. | 11.00 | Week 01, 2013 | SD | HouHou | 33 Rush, 22 Receiving, 1 TD |
| 33. | 11.00 | Week 01, 2011 | SD | MinMin | 45 Rush, 73 Receiving |
| 33. | 11.00 | Week 08, 2010 | SD | TenTen | 43 Rush, 11 Receiving, 1 TD |
| 36. | 10.00 | Week 10, 2015 | Phi | MiaMia | 18 Rush, 22 Receiving, 1 TD |
| 36. | 10.00 | Week 13, 2014 | SD | @Bal@Bal | 40 Rush, 6 Receiving, 1 TD |
| 36. | 10.00 | Week 06, 2013 | SD | IndInd | 102 Rush |
| 36. | 10.00 | Week 04, 2013 | SD | DalDal | 62 Rush, 41 Receiving |
| 36. | 10.00 | Week 08, 2011 | SD | @KC@KC | 57 Rush, 55 Receiving, 1 Fumb |
| 41. | 9.00 | Week 13, 2013 | SD | CinCin | 61 Rush, 31 Receiving |
| 41. | 9.00 | Week 08, 2012 | SD | @Cle@Cle | 95 Rush, 9 Receiving, 1 Fumb |
| 41. | 9.00 | Week 06, 2012 | SD | DenDen | 74 Rush, 19 Receiving |
| 44. | 8.00 | Week 01, 2015 | Phi | @Atl@Atl | 4 Rush, 24 Receiving, 1 TD |
| 44. | 8.00 | Week 12, 2012 | SD | BalBal | 72 Rush, 16 Receiving |
| 44. | 8.00 | Week 11, 2012 | SD | @Den@Den | 47 Rush, 36 Receiving |
| 44. | 8.00 | Week 04, 2012 | SD | @KC@KC | 61 Rush, 21 Receiving |
| 48. | 7.00 | Week 09, 2016 | Phi | @NYG@NYG | 15 Rush, 1 TD |
| 48. | 7.00 | Week 08, 2016 | Phi | @Dal@Dal | 10 Rush, 1 Receiving, 1 TD |
| 48. | 7.00 | Week 07, 2016 | Phi | MinMin | 56 Rush, 27 Receiving, 1 Fumb |