*=Defensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 16.00 | Week 04, 2013 | Buf | BalBal | 2 Tackles, 2 Int, 4 PD |
| 2. | 14.00 | Week 03, 2014 | Buf | SDSD | 9 Tackles, 5 Assists |
| 3. | 13.00 | Week 15, 2013 | Buf | @Jac@Jac | 4 Tackles, 1 Int, 1 FF, 1 PD |
| 4. | 12.00 | Week 01, 2015 | Buf | IndInd | 1 Tackle, 4 Assists, 1 Int, 2 PD |
| 4. | 12.00 | Week 07, 2013 | Buf | @Mia@Mia | 6 Tackles, 1 Int, 1 PD |
| 4. | 12.00 | Week 02, 2013 | Buf | CarCar | 7 Tackles, 5 Assists |
| 4. | 12.00 | Week 16, 2011 | Buf | DenDen | 4 Tackles, 1 Assist, 1 Int, 2 PD |
| 8. | 11.00 | Week 11, 2013 | Buf | NYJNYJ | 6 Tackles, 4 Assists, 1 PD |
| 9. | 10.00 | Week 03, 2016 | Buf | AriAri | 1 TD, 1 Fum Rcvy, 1 PD |
| 9. | 10.00 | Week 15, 2011 | Buf | MiaMia | 6 Tackles, 1 FF, 1 PD |
| 11. | 9.00 | Week 15, 2014 | Buf | GBGB | 5 Tackles, 4 Assists |
| 11. | 9.00 | Week 13, 2014 | Buf | CleCle | 4 Tackles, 5 Assists |
| 11. | 9.00 | Week 09, 2013 | Buf | KCKC | 7 Tackles, 1 Assist, 1 PD |
| 11. | 9.00 | Week 01, 2013 | Buf | NENE | 4 Tackles, 5 Assists |
| 15. | 8.00 | Week 02, 2014 | Buf | MiaMia | 7 Tackles, 1 PD |
| 15. | 8.00 | Week 13, 2013 | Buf | AtlAtl | 6 Tackles, 1 Assist, 1 PD |
| 17. | 7.00 | Week 02, 2016 | Buf | NYJNYJ | 3 Tackles, 3 Assists, 1 PD |
| 17. | 7.00 | Week 05, 2015 | Buf | @Ten@Ten | 5 Tackles, 2 Assists |
| 17. | 7.00 | Week 08, 2014 | Buf | @NYJ@NYJ | 1 Tackle, 1 Int, 1 PD |
| 17. | 7.00 | Week 17, 2012 | Buf | NYJNYJ | 5 Tackles, 2 PD |
| 21. | 6.00 | Week 16, 2014 | Buf | @Oak@Oak | 5 Tackles, 1 Assist |
| 21. | 6.00 | Week 10, 2013 | Buf | @Pit@Pit | 5 Tackles, 1 PD |
| 21. | 6.00 | Week 08, 2013 | Buf | @NO@NO | 4 Tackles, 2 Assists |
| 24. | 5.00 | Week 04, 2016 | Buf | @NE@NE | 2 Tackles, 3 PD |
| 24. | 5.00 | Week 17, 2014 | Buf | @NE@NE | 2 Tackles, 2 Assists, 1 PD |
| 24. | 5.00 | Week 05, 2013 | Buf | @Cle@Cle | 4 Tackles, 1 Assist |
| 24. | 5.00 | Week 05, 2012 | Buf | @SF@SF | 2 Tackles, 3 Assists |
| 24. | 5.00 | Week 01, 2012 | Buf | @NYJ@NYJ | 2 Tackles, 1 FF |
| 24. | 5.00 | Week 13, 2011 | Buf | TenTen | 3 Tackles, 1 Assist, 1 PD |
| 24. | 5.00 | Week 03, 2011 | Buf | NENE | 4 Tackles, 1 Assist |
| 24. | 5.00 | Week 02, 2011 | Buf | OakOak | 1 Tackle, 4 Assists |
| 32. | 4.00 | Week 07, 2016 | Buf | @Mia@Mia | 2 Tackles, 2 Assists |
| 32. | 4.00 | Week 02, 2015 | Buf | NENE | 3 Tackles, 1 PD |
| 32. | 4.00 | Week 11, 2014 | Buf | @Mia@Mia | 4 Tackles |
| 32. | 4.00 | Week 05, 2014 | Buf | @Det@Det | 2 Tackles, 2 Assists |
| 32. | 4.00 | Week 04, 2014 | Buf | @Hou@Hou | 3 Tackles, 1 PD |
| 32. | 4.00 | Week 03, 2013 | Buf | @NYJ@NYJ | 3 Tackles, 1 Assist |
| 32. | 4.00 | Week 09, 2012 | Buf | @Hou@Hou | 3 Tackles, 1 Assist |
| 32. | 4.00 | Week 07, 2012 | Buf | TenTen | 3 Tackles, 1 PD |
| 32. | 4.00 | Week 04, 2012 | Buf | NENE | 1 Tackle, 2 Assists, 1 PD |
| 32. | 4.00 | Week 03, 2012 | Buf | @Cle@Cle | 1 Tackle, 1 Assist, 2 PD |
| 32. | 4.00 | Week 02, 2012 | Buf | KCKC | 3 Tackles, 1 PD |
| 43. | 3.00 | Week 06, 2016 | Buf | SFSF | 2 Tackles, 1 Assist |
| 43. | 3.00 | Week 01, 2016 | Buf | @Bal@Bal | 3 Tackles |
| 43. | 3.00 | Week 14, 2014 | Buf | @Den@Den | 2 Tackles, 1 Assist |
| 43. | 3.00 | Week 12, 2014 | Buf | NYJNYJ | 1 Tackle, 1 Assist, 1 PD |
| 43. | 3.00 | Week 10, 2014 | Buf | KCKC | 1 Tackle, 2 Assists |
| 43. | 3.00 | Week 07, 2014 | Buf | MinMin | 2 Tackles, 1 Assist |
| 43. | 3.00 | Week 01, 2014 | Buf | @CHI@CHI | 2 Tackles, 1 Assist |
| 43. | 3.00 | Week 06, 2013 | Buf | CinCin | 1 Tackle, 1 Assist, 1 PD |