*=Defensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 25.00 | Week 03, 2015 * | Buf | @Mia@Mia | 3 Tackles, 4 Assists, 2 Int, 1 TD, 2 PD |
| 2. | 19.00 | Week 02, 2016 | Buf | NYJNYJ | 7 Tackles, 9 Assists, 1 FF |
| 2. | 19.00 | Week 02, 2015 | Buf | NENE | 8 Tackles, 5 Assists, 1 FF, 1 Fum Rcvy |
| 4. | 15.00 | Week 16, 2016 | Buf | MiaMia | 9 Tackles, 6 Assists |
| 4. | 15.00 | Week 08, 2014 | Buf | @NYJ@NYJ | 8 Tackles, 1 Assist, 1 Int, 1 PD |
| 6. | 14.00 | Week 02, 2019 | Cin | SFSF | |
| 6. | 14.00 | Week 16, 2017 | Buf | @NE@NE | 9 Tackles, 5 Assists |
| 6. | 14.00 | Week 17, 2016 | Buf | @NYJ@NYJ | 5 Tackles, 9 Assists |
| 9. | 13.00 | Week 08, 2018 | Cin | TBTB | 5 Tackles, 2 Assists, 1 Int, 1 PD |
| 9. | 13.00 | Week 11, 2017 | Buf | @LAC@LAC | 11 Tackles, 2 Assists |
| 9. | 13.00 | Week 08, 2016 | Buf | NENE | 8 Tackles, 1 Assist, 1.0 Sack |
| 9. | 13.00 | Week 02, 2014 | Buf | MiaMia | 7 Tackles, 6 Assists |
| 13. | 12.00 | Week 17, 2017 | Buf | @Mia@Mia | 7 Tackles, 5 Assists |
| 13. | 12.00 | Week 12, 2016 | Buf | JacJac | 5 Tackles, 7 Assists |
| 13. | 12.00 | Week 13, 2014 | Buf | CleCle | 7 Tackles, 4 Assists, 1 PD |
| 16. | 11.00 | Week 01, 2018 | Cin | @Ind@Ind | 5 Tackles, 1 Int, 1 PD |
| 16. | 11.00 | Week 07, 2017 | Buf | TBTB | 5 Tackles, 6 Assists |
| 16. | 11.00 | Week 14, 2016 | Buf | PitPit | 7 Tackles, 4 Assists |
| 16. | 11.00 | Week 04, 2016 | Buf | @NE@NE | 3 Tackles, 5 Assists, 1 Fum Rcvy |
| 16. | 11.00 | Week 01, 2016 | Buf | @Bal@Bal | 6 Tackles, 2 Assists, 1 Fum Rcvy |
| 16. | 11.00 | Week 15, 2015 | Buf | @Was@Was | 4 Tackles, 7 Assists |
| 16. | 11.00 | Week 04, 2015 | Buf | NYGNYG | 6 Tackles, 5 Assists |
| 16. | 11.00 | Week 03, 2014 | Buf | SDSD | 4 Tackles, 7 Assists |
| 24. | 10.00 | Week 10, 2018 | Cin | NONO | 5 Tackles, 4 Assists, 1 PD |
| 24. | 10.00 | Week 15, 2017 | Buf | MiaMia | 7 Tackles, 3 Assists |
| 24. | 10.00 | Week 04, 2017 | Buf | @Atl@Atl | 5 Tackles, 5 Assists |
| 24. | 10.00 | Week 03, 2017 | Buf | DenDen | 4 Tackles, 6 Assists |
| 24. | 10.00 | Week 11, 2015 | Buf | @NE@NE | 5 Tackles, 5 Assists |
| 24. | 10.00 | Week 09, 2015 | Buf | MiaMia | 7 Tackles, 2 Assists, 1 PD |
| 24. | 10.00 | Week 01, 2014 | Buf | @CHI@CHI | 5 Tackles, 2 Assists, 1 Fum Rcvy |
| 31. | 9.00 | Week 03, 2019 | Cin | @Buf@Buf | 6 Tackles, 1 Fum Rcvy |
| 31. | 9.00 | Week 13, 2017 | Buf | NENE | 5 Tackles, 3 Assists, 1 PD |
| 31. | 9.00 | Week 12, 2017 | Buf | @KC@KC | 6 Tackles, 3 Assists |
| 31. | 9.00 | Week 08, 2017 | Buf | OakOak | 3 Tackles, 4 Assists, 2 PD |
| 31. | 9.00 | Week 06, 2016 | Buf | SFSF | 6 Tackles, 3 Assists |
| 31. | 9.00 | Week 13, 2015 | Buf | HouHou | 5 Tackles, 4 Assists |
| 31. | 9.00 | Week 06, 2015 | Buf | CinCin | 7 Tackles, 2 Assists |
| 31. | 9.00 | Week 04, 2014 | Buf | @Hou@Hou | 5 Tackles, 4 Assists |
| 39. | 8.00 | Week 06, 2018 | Cin | PitPit | 3 Tackles, 5 Assists |
| 39. | 8.00 | Week 09, 2017 | Buf | @NYJ@NYJ | 5 Tackles, 3 Assists |
| 39. | 8.00 | Week 05, 2017 | Buf | @Cin@Cin | 4 Tackles, 4 Assists |
| 39. | 8.00 | Week 10, 2015 | Buf | @NYJ@NYJ | 3 Tackles, 5 Assists |
| 39. | 8.00 | Week 10, 2014 | Buf | KCKC | 6 Tackles, 2 Assists |
| 44. | 7.00 | Week 04, 2019 | Cin | @Pit@Pit | 5 Tackles, 2 Assists |
| 44. | 7.00 | Week 01, 2019 | Cin | @Sea@Sea | 1 Tackle, 3 Assists, 1 FF |
| 44. | 7.00 | Week 14, 2017 | Buf | IndInd | 6 Tackles, 1 Assist |
| 44. | 7.00 | Week 02, 2017 | Buf | @Car@Car | 7 Assists |
| 44. | 7.00 | Week 13, 2016 | Buf | @Oak@Oak | 4 Tackles, 3 Assists |
| 44. | 7.00 | Week 05, 2016 | Buf | @LA@LA | 6 Tackles, 1 Assist |
| 44. | 7.00 | Week 16, 2015 | Buf | DalDal | 3 Tackles, 4 Assists |