*=Defensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 27.00 | Week 17, 2006 | SF | @Den@Den | 2 Tackles, 2 Assists, 2 Int, 1 TD, 1 Fum Rcvy, 4 PD |
| 2. | 22.00 | Week 05, 2006 | SF | OakOak | 4 Tackles, 3 Int3 PD |
| 3. | 19.00 | Week 02, 1997 | Chi | @Min@Min | 12 Tackles, 2 Assists, 1 Int |
| 4. | 18.00 | Week 01, 2006 | SF | @Ari@Ari | 5 Tackles, 1 Assist, 1.0 Sack, 1 FF, 1 Fum Rcvy, 2 PD |
| 4. | 18.00 | Week 16, 2001 | Chi | @Det@Det | 4 Tackles, 1 Int, 1 TD, 1 Fum Rcvy |
| 6. | 17.00 | Week 10, 1999 | Chi | MinMin | 9 Tackles, 3 Assists, 1 Int |
| 7. | 15.00 | Week 11, 2008 | SF | StLStL | 3 Tackles, 1.0 Sack, 1 Int, 3 PD |
| 7. | 15.00 | Week 12, 2007 | SF | @Ari@Ari | 3 Tackles, 2 Int, 2 PD |
| 7. | 15.00 | Week 09, 1999 | Chi | @GB@GB | 11 Tackles, 1.0 Sack |
| 7. | 15.00 | Week 15, 1998 | Chi | @GB@GB | 4 Tackles, 1 Int, 1 TD |
| 11. | 14.00 | Week 12, 2005 | Was | SDSD | 8 Tackles, 1 Int1 PD |
| 12. | 13.00 | Week 01, 2007 | SF | AriAri | 4 Tackles, 1 Assist, 1 Int, 3 PD |
| 12. | 13.00 | Week 05, 2002 | Ind | CinCin | 3 Tackles, 2 Int |
| 12. | 13.00 | Week 10, 2000 | Chi | IndInd | 1 Tackle, 1 Assist, 1 Int, 1 TD |
| 15. | 12.00 | Week 02, 2008 | SF | @Sea@Sea | 4 Tackles, 1 Int, 3 PD |
| 15. | 12.00 | Week 11, 2006 | SF | SeaSea | 2 Int2 PD |
| 17. | 11.00 | Week 16, 1997 | Chi | StLStL | 1 Tackle, 2 Int |
| 17. | 11.00 | Week 11, 1997 | Chi | MinMin | 6 Tackles, 1 Int |
| 19. | 10.00 | Week 14, 2008 | SF | NYJNYJ | 2 Tackles, 2 Assists, 1 Int, 1 PD |
| 19. | 10.00 | Week 07, 2008 | SF | @NYG@NYG | 6 Tackles, 3 Assists, 1 PD |
| 19. | 10.00 | Week 02, 2006 | SF | StLStL | 7 Tackles, 3 PD |
| 19. | 10.00 | Week 08, 2005 | Was | @NYG@NYG | 6 Tackles, 4 Assists |
| 19. | 10.00 | Week 15, 2004 | Was | @SF@SF | 4 Tackles, 1 Int1 PD |
| 19. | 10.00 | Week 06, 2003 | Ind | CarCar | 5 Tackles, 1 Assist, 1 Fum Rcvy, 1 PD |
| 19. | 10.00 | Week 14, 1998 | Chi | @Min@Min | 5 Tackles, 1 Int |
| 19. | 10.00 | Week 06, 1998 | Chi | @Ari@Ari | 5 Tackles, 1 Int |
| 19. | 10.00 | Week 03, 1997 | Chi | @Det@Det | 9 Tackles, 1 Assist |
| 28. | 9.00 | Week 17, 2007 | SF | @Cle@Cle | 1 Tackle, 1 Assist, 1 Int, 2 PD |
| 28. | 9.00 | Week 08, 2006 | SF | @Chi@Chi | 5 Tackles, 1 FF, 1 PD |
| 28. | 9.00 | Week 17, 2005 | Was | @Phi@Phi | 5 Tackles, 4 PD |
| 28. | 9.00 | Week 01, 2003 | Ind | @Cle@Cle | 5 Tackles, 1 Assist, 1 FF |
| 28. | 9.00 | Week 08, 1998 | Chi | @Ten@Ten | 4 Tackles, 1 Int |
| 28. | 9.00 | Week 03, 1998 | Chi | @TB@TB | 5 Tackles, 1 Assist, 1 Fum Rcvy |
| 28. | 9.00 | Week 07, 1997 | Chi | @GB@GB | 4 Tackles, 1 Int |
| 35. | 8.00 | Week 14, 2007 | SF | MinMin | 5 Tackles, 1 FF |
| 35. | 8.00 | Week 12, 2006 | SF | @StL@StL | 6 Tackles, 2 PD |
| 35. | 8.00 | Week 09, 2006 | SF | MinMin | 2 Tackles, 1 Int1 PD |
| 35. | 8.00 | Week 03, 2003 | Ind | JacJac | 3 Tackles, 2 Assists, 3 PD |
| 35. | 8.00 | Week 10, 2002 | Ind | @Phi@Phi | 2 Tackles, 3 Assists, 1 Fum Rcvy |
| 35. | 8.00 | Week 11, 2000 | Chi | @Buf@Buf | 2 Tackles, 1 Assist, 1 Int |
| 35. | 8.00 | Week 05, 2000 | Chi | @GB@GB | 6 Tackles, 2 Assists |
| 35. | 8.00 | Week 06, 1999 | Chi | PhiPhi | 6 Tackles, 2 Assists |
| 35. | 8.00 | Week 01, 1998 | Chi | JacJac | 8 Tackles |
| 35. | 8.00 | Week 13, 1997 | Chi | @TB@TB | 5 Tackles, 1 Fum Rcvy |
| 45. | 7.00 | Week 06, 2008 | SF | PhiPhi | 6 Tackles, 1 PD |
| 45. | 7.00 | Week 08, 2007 | SF | NONO | 6 Tackles, 1 PD |
| 45. | 7.00 | Week 05, 2007 | SF | BalBal | 3 Tackles, 3 Assists, 1 PD |
| 45. | 7.00 | Week 02, 2007 | SF | @StL@StL | 5 Tackles, 2 PD |
| 45. | 7.00 | Week 14, 2006 | SF | GBGB | 4 Tackles, 2 Assists, 1 PD |
| 45. | 7.00 | Week 03, 2006 | SF | PhiPhi | 2 Tackles, 2 Assists, 1 FF |