*=Offensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 60.00 | Week 01, 2013 * | Den | BalBal | 462 Pass, - 2 Rush, 7 TD |
| 2. | 48.00 | Week 04, 2003 * | Ind | @NO@NO | 314 Pass, 1 Rush, 6 TD |
| 3. | 46.00 | Week 08, 2004 * | Ind | @KC@KC | 472 Pass, 5 TD, 1 Int |
| 4. | 45.00 | Week 12, 2004 * | Ind | @Det@Det | 236 Pass, 4 Rush, 6 TD |
| 4. | 45.00 | Week 03, 2004 * | Ind | GBGB | 393 Pass, - 2 Rush, 5 TD |
| 6. | 44.00 | Week 05, 2013 | Den | @Dal@Dal | 414 Pass, - 8 Rush, 5 TD, 1 Int |
| 6. | 44.00 | Week 02, 2001 * | Ind | BufBuf | 421 Pass, 26 Rush, 5 TD, 2 Int |
| 8. | 42.00 | Week 13, 2013 * | Den | @KC@KC | 403 Pass, - 3 Rush, 5 TD, 2 Int |
| 9. | 41.00 | Week 15, 2003 | Ind | AtlAtl | 290 Pass, 5 TD |
| 10. | 40.00 | Week 16, 2013 | Den | @Hou@Hou | 400 Pass, 4 TD |
| 10. | 40.00 | Week 04, 2000 * | Ind | JacJac | 440 Pass, 4 Rush, 4 TD, 1 Fumb |
| 12. | 39.00 | Week 10, 2014 | Den | @Oak@Oak | 340 Pass, 5 TD, 2 Int |
| 12. | 39.00 | Week 05, 2014 * | Den | AriAri | 479 Pass, - 2 Rush, 4 TD, 2 Int |
| 12. | 39.00 | Week 14, 2013 | Den | TenTen | 397 Pass, - 1 Rush, 4 TD |
| 15. | 38.00 | Week 10, 2004 | Ind | HouHou | 320 Pass, 5 TD, 2 Int |
| 16. | 37.00 | Week 04, 2013 | Den | PhiPhi | 327 Pass, 4 TD |
| 16. | 37.00 | Week 03, 2009 * | Ind | @Ari@Ari | 379 Pass, - 1 Rush, 4 TD, 1 Int |
| 16. | 37.00 | Week 07, 2006 * | Ind | WasWas | 342 Pass, - 1 Rush, 4 TD |
| 19. | 36.00 | Week 12, 2014 * | Den | MiaMia | 257 Pass, - 2 Rush, 4 TD, 1 2-Pt |
| 19. | 36.00 | Week 07, 2014 | Den | SFSF | 318 Pass, - 1 Rush, 4 TD |
| 19. | 36.00 | Week 10, 2013 | Den | @SD@SD | 330 Pass, - 1 Rush, 4 TD, 1 Fumb |
| 19. | 36.00 | Week 15, 2006 | Ind | CinCin | 282 Pass, 10 Rush, 4 TD |
| 19. | 36.00 | Week 09, 2004 * | Ind | MinMin | 268 Pass, 20 Rush, 4 TD |
| 24. | 35.00 | Week 01, 2010 | Ind | @Hou@Hou | 433 Pass, 3 TD |
| 25. | 34.00 | Week 17, 2013 | Den | @Oak@Oak | 266 Pass, 4 TD |
| 25. | 34.00 | Week 15, 2009 | Ind | @Jac@Jac | 308 Pass, - 3 Rush, 4 TD, 1 Int |
| 25. | 34.00 | Week 02, 2006 | Ind | HouHou | 400 Pass, 2 Rush, 3 TD |
| 25. | 34.00 | Week 04, 2005 | Ind | @Ten@Ten | 264 Pass, 3 Rush, 4 TD |
| 29. | 33.00 | Week 11, 2010 | Ind | @NE@NE | 396 Pass, 4 TD, 3 Int |
| 29. | 33.00 | Week 10, 2009 | Ind | NENE | 327 Pass, 4 TD, 2 Int |
| 29. | 33.00 | Week 14, 2007 | Ind | @Bal@Bal | 249 Pass, 4 TD |
| 29. | 33.00 | Week 13, 2007 | Ind | JacJac | 288 Pass, 2 Rush, 4 TD, 1 Int |
| 29. | 33.00 | Week 08, 2006 | Ind | @Den@Den | 345 Pass, - 1 Rush, 3 TD, 1 2-Pt |
| 29. | 33.00 | Week 17, 2000 | Ind | MinMin | 283 Pass, -1 Rush, 4 TD, 1 Int |
| 29. | 33.00 | Week 03, 1999 | Ind | @SD@SD | 404 Pass, 14 Rush, 3 TD, 1 Int |
| 36. | 32.00 | Week 16, 2008 | Ind | @Jac@Jac | 364 Pass, 1 Rush, 3 TD |
| 36. | 32.00 | Week 07, 2004 | JacJac | 368 Pass, 3 TD | |
| 36. | 32.00 | Week 13, 2003 | Ind | NENE | 278 Pass, 1 Rush, 4 TD, 1 Int, 1 Fumb |
| 39. | 31.00 | Week 08, 2013 | Den | WasWas | 354 Pass, - 3 Rush, 4 TD, 3 Int, 1 Fumb |
| 39. | 31.00 | Week 07, 2013 | Den | @Ind@Ind | 386 Pass, - 1 Rush, 3 TD, 1 Int |
| 39. | 31.00 | Week 03, 2013 | Den | OakOak | 374 Pass, - 2 Rush, 3 TD, 1 Fumb |
| 39. | 31.00 | Week 04, 2012 | Den | OakOak | 338 Pass, - 1 Rush, 3 TD |
| 39. | 31.00 | Week 03, 2010 | Ind | @Den@Den | 325 Pass, - 1 Rush, 3 TD |
| 39. | 31.00 | Week 04, 2007 | Ind | DenDen | 193 Pass, - 3 Rush, 4 TD |
| 39. | 31.00 | Week 10, 2002 | Ind | @Phi@Phi | 319 Pass, 11 Rush, 3 TD |
| 46. | 30.00 | Week 17, 2012 | Den | KCKC | 304 Pass, 3 TD |
| 46. | 30.00 | Week 08, 2012 | Den | NONO | 305 Pass, 4 Rush, 3 TD |
| 46. | 30.00 | Week 05, 2012 | Den | @NE@NE | 345 Pass, 9 Rush, 3 TD, 1 Fumb |
| 46. | 30.00 | Week 16, 2007 | Ind | HouHou | 311 Pass, - 1 Rush, 3 TD |
| 46. | 30.00 | Week 17, 2006 | Ind | MiaMia | 282 Pass, 11 Rush, 3 TD |