*=Defensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 16.00 | Week 17, 2004 | SF | @NE@NE | 2 Tackles, 1 Assist, 1.0 Sack, 2 FF, 1 Fum Rcvy |
| 2. | 14.00 | Week 13, 2004 | SF | @StL@StL | 2 Tackles, 1 Assist, 2.0 Sacks, 1 FF |
| 3. | 11.00 | Week 13, 2003 | SF | @Bal@Bal | 1 Tackle, 1.0 Sack, 1 FF, 1 Fum Rcvy |
| 4. | 10.00 | Week 02, 2004 | SF | @NO@NO | 1 Tackle, 1 Assist, 1.0 Sack, 1 FF, 1 PD |
| 5. | 9.00 | Week 15, 2006 | Den | @Ari@Ari | 2 Tackles, 1.0 Sack, 1 FF |
| 6. | 8.00 | Week 04, 2003 | SF | @Min@Min | 4 Tackles, 1.0 Sack |
| 6. | 8.00 | Week 11, 2001 | SF | @Ind@Ind | 4 Tackles, 1.0 Sack |
| 6. | 8.00 | Week 09, 2000 | SF | StLStL | 4 Tackles, 1.0 Sack |
| 6. | 8.00 | Week 03, 2000 | SF | @StL@StL | 4 Tackles, 1.0 Sack |
| 10. | 7.00 | Week 03, 2008 | Den | NONO | 4 Tackles, 1 FF |
| 10. | 7.00 | Week 07, 2007 | Den | PitPit | 1 Tackle, 2 Assists, 1.0 Sack |
| 10. | 7.00 | Week 10, 2006 | Den | @Oak@Oak | 2 Tackles, 2 Assists, 1 Fum Rcvy |
| 10. | 7.00 | Week 09, 2004 | SF | SeaSea | 2 Tackles, 1.0 Sack, 1 PD |
| 14. | 6.00 | Week 01, 2008 | Den | @Oak@Oak | 6 Tackles |
| 14. | 6.00 | Week 03, 2004 | SF | @Sea@Sea | 3 Tackles, 1 Assist, 0.5 Sack |
| 14. | 6.00 | Week 03, 2003 | SF | CleCle | 2 Tackles, 1.0 Sack |
| 14. | 6.00 | Week 15, 2001 | SF | PhiPhi | 2 Tackles, 1.0 Sack |
| 14. | 6.00 | Week 08, 2001 | SF | DetDet | 2 Tackles, 1.0 Sack |
| 14. | 6.00 | Week 02, 2001 | SF | StLStL | 2 Tackles, 1.0 Sack |
| 20. | 5.00 | Week 02, 2008 | Den | SDSD | 1 Tackle, 1.0 Sack |
| 20. | 5.00 | Week 17, 2007 | Den | MinMin | 2 Tackles, 1 FF |
| 20. | 5.00 | Week 13, 2007 | Den | @Oak@Oak | 5 Tackles |
| 20. | 5.00 | Week 01, 2007 | Den | @Buf@Buf | 2 Tackles, 3 Assists |
| 20. | 5.00 | Week 17, 2006 | Den | SFSF | 4 Tackles, 1 PD |
| 20. | 5.00 | Week 02, 2006 | Den | KCKC | 2 Tackles, 1 FF |
| 20. | 5.00 | Week 05, 2005 | Den | WasWas | 4 Tackles, 1 Assist |
| 20. | 5.00 | Week 06, 2004 | SF | @NYJ@NYJ | 3 Tackles, 2 Assists |
| 20. | 5.00 | Week 16, 2003 | SF | @Phi@Phi | 1 Tackle, 1.0 Sack |
| 20. | 5.00 | Week 11, 2003 | SF | PitPit | 5 Tackles |
| 20. | 5.00 | Week 02, 2003 | SF | @StL@StL | 2 Tackles, 1 Fum Rcvy |
| 20. | 5.00 | Week 16, 2001 | SF | @Dal@Dal | 5 Tackles |
| 20. | 5.00 | Week 04, 2000 | SF | @Dal@Dal | 1 Tackle, 1.0 Sack |
| 33. | 4.00 | Week 12, 2008 | Den | OakOak | 1 Tackle, 3 Assists |
| 33. | 4.00 | Week 15, 2007 | Den | @Hou@Hou | 3 Tackles, 1 Assist |
| 33. | 4.00 | Week 12, 2007 | Den | @Chi@Chi | 3 Tackles, 1 PD |
| 33. | 4.00 | Week 02, 2007 | Den | OakOak | 4 Tackles |
| 33. | 4.00 | Week 13, 2006 | Den | SeaSea | 1 Tackle, 2 Assists, 1 PD |
| 33. | 4.00 | Week 15, 2004 | SF | WasWas | 2 Tackles, 2 Assists |
| 33. | 4.00 | Week 14, 2004 | SF | @Ari@Ari | 3 Tackles, 1 Assist |
| 33. | 4.00 | Week 12, 2004 | SF | MiaMia | 2 Tackles, 2 Assists |
| 33. | 4.00 | Week 08, 2004 | SF | @Chi@Chi | 1 Tackle, 3 Assists |
| 33. | 4.00 | Week 03, 2001 | SF | @NYJ@NYJ | 3 Tackles, 1 Assist |
| 33. | 4.00 | Week 17, 2000 | SF | @Den@Den | 1 Tackle, 3 Assists |
| 33. | 4.00 | Week 11, 2000 | SF | KCKC | 3 Tackles, 1 Assist |
| 33. | 4.00 | Week 07, 2000 | SF | @GB@GB | 2 Tackles, 2 Assists |
| 46. | 3.00 | Week 17, 2008 | Den | @SD@SD | 2 Tackles, 1 Assist |
| 46. | 3.00 | Week 13, 2008 | Den | @NYJ@NYJ | 2 Tackles, 1 Assist |
| 46. | 3.00 | Week 04, 2008 | Den | @KC@KC | 2 Tackles, 1 Assist |
| 46. | 3.00 | Week 11, 2007 | Den | TenTen | 3 Tackles |
| 46. | 3.00 | Week 05, 2007 | Den | SDSD | 3 Tackles |