*=Defensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 25.00 | Week 17, 2010 | SF | AriAri | 8 Tackles, 2 Assists, 3.0 Sacks, 1 FF |
| 2. | 23.00 | Week 01, 2006 * | Cin | @KC@KC | 5 Tackles, 3.0 Sacks, 1 FF, 1 Fum Rcvy |
| 3. | 22.00 | Week 17, 2009 | SF | @StL@StL | 8 Tackles, 3.5 Sacks |
| 4. | 20.00 | Week 13, 2001 | Cin | JacJac | 5 Tackles, 3 Assists, 3.0 Sacks |
| 5. | 17.00 | Week 12, 2009 | SF | JacJac | 3 Tackles, 2 Assists, 1.5 Sacks, 1 FF, 1 Fum Rcvy |
| 5. | 17.00 | Week 03, 2008 | SF | DetDet | 3 Tackles, 1 Assist, 1.0 Sack, 1 Int, 1 FF, 1 PD |
| 5. | 17.00 | Week 07, 2004 | DenDen | 4 Tackles, 2 Assists, 2.0 Sacks, 1 FF | |
| 8. | 14.00 | Week 01, 2014 | SF | @DAL@DAL | 4 Tackles, 2 Assists, 2.0 Sacks |
| 8. | 14.00 | Week 08, 2006 | Cin | AtlAtl | 5 Tackles, 7 Assists, 0.5 Sack |
| 8. | 14.00 | Week 11, 2004 | Cin | PitPit | 6 Tackles, 1 Assist, 1.0 Sack, 1 Fum Rcvy |
| 11. | 13.00 | Week 06, 2011 | SF | @Det@Det | 5 Tackles, 2 Assists, 1.5 Sacks |
| 11. | 13.00 | Week 17, 2004 | Cin | @Phi@Phi | 2 Tackles, 1 Assist, 1.0 Sack, 1 FF, 1 Fum Rcvy |
| 13. | 12.00 | Week 13, 2012 | SF | @StL@StL | 8 Tackles, 1.0 Sack |
| 13. | 12.00 | Week 01, 2011 | SF | SeaSea | 4 Tackles, 2.0 Sacks |
| 13. | 12.00 | Week 08, 2010 | SF | DenDen | 4 Tackles, 2.0 Sacks |
| 13. | 12.00 | Week 05, 2010 | SF | PhiPhi | 4 Tackles, 2.0 Sacks |
| 13. | 12.00 | Week 16, 2003 | Cin | @StL@StL | 7 Tackles, 1 Assist, 1.0 Sack |
| 13. | 12.00 | Week 16, 2002 | Cin | NONO | 4 Tackles, 2.0 Sacks |
| 13. | 12.00 | Week 12, 2001 | Cin | TBTB | 4 Tackles, 2.0 Sacks |
| 20. | 11.00 | Week 07, 2013 | SF | @Ten@Ten | 3 Tackles, 2.0 Sacks |
| 20. | 11.00 | Week 14, 2011 | SF | @Ari@Ari | 4 Tackles, 1.0 Sack, 1 FF |
| 20. | 11.00 | Week 17, 2008 | SF | WasWas | 5 Tackles, 1 Assist, 1.0 Sack, 1 PD |
| 20. | 11.00 | Week 13, 2008 | SF | @Buf@Buf | 3 Tackles, 2 Assists, 1.5 Sacks |
| 20. | 11.00 | Week 06, 2007 | Cin | @KC@KC | 4 Tackles, 1 Assist, 1.5 Sacks |
| 20. | 11.00 | Week 04, 2005 | Cin | HouHou | 2 Tackles, 2 Assists, 1.0 Sack, 1 FF |
| 20. | 11.00 | Week 04, 2003 | Cin | @Cle@Cle | 3 Tackles, 2 Assists, 1.0 Sack, 2 PD |
| 27. | 10.00 | Week 12, 2014 | SF | WasWas | 3 Tackles, 1.0 Sack, 1 FF |
| 27. | 10.00 | Week 12, 2012 | SF | @NO@NO | 2 Tackles, 2 Assists, 1.5 Sacks |
| 27. | 10.00 | Week 10, 2010 | SF | StLStL | 5 Tackles, 1 Assist, 1.0 Sack |
| 27. | 10.00 | Week 07, 2009 | SF | @Hou@Hou | 8 Tackles, 2 Assists |
| 27. | 10.00 | Week 16, 2008 | SF | @StL@StL | 6 Tackles, 1.0 Sack |
| 27. | 10.00 | Week 05, 2008 | SF | NENE | 1 Tackle, 5 Assists, 1.0 Sack |
| 27. | 10.00 | Week 08, 2007 | Cin | PitPit | 8 Tackles, 2 Assists |
| 27. | 10.00 | Week 09, 2006 | Cin | @Bal@Bal | 6 Tackles, 4 Assists |
| 27. | 10.00 | Week 06, 2006 | Cin | @TB@TB | 4 Tackles, 2 Assists, 1.0 Sack |
| 27. | 10.00 | Week 04, 2006 | Cin | NENE | 5 Tackles, 5 Assists |
| 27. | 10.00 | Week 03, 2006 | Cin | @Pit@Pit | 3 Tackles, 2 Assists, 1.0 Sack, 1 PD |
| 27. | 10.00 | Week 16, 2005 | Cin | BufBuf | 3 Tackles, 2 Assists, 1.0 Sack, 1 PD |
| 27. | 10.00 | Week 17, 2001 | Cin | @Ten@Ten | 5 Tackles, 1 Assist, 1.0 Sack |
| 27. | 10.00 | Week 10, 2001 | Cin | TenTen | 4 Tackles, 4 Assists, 0.5 Sack |
| 41. | 9.00 | Week 16, 2013 | SF | AtlAtl | 4 Tackles, 1 Assist, 1.0 Sack |
| 41. | 9.00 | Week 12, 2013 | SF | @Was@Was | 4 Tackles, 2 Assists, 1 FF |
| 41. | 9.00 | Week 02, 2013 | SF | @Sea@Sea | 4 Tackles, 5 Assists |
| 41. | 9.00 | Week 07, 2012 | SF | SeaSea | 7 Tackles, 2 Assists |
| 41. | 9.00 | Week 01, 2008 | SF | AriAri | 3 Tackles, 4 Assists, 0.5 Sack |
| 41. | 9.00 | Week 02, 2007 | Cin | @Cle@Cle | 6 Tackles, 3 Assists |
| 41. | 9.00 | Week 11, 2005 | Cin | IndInd | 3 Tackles, 2 Assists, 1.0 Sack |
| 41. | 9.00 | Week 02, 2005 | Cin | MinMin | 2 Tackles, 1.0 Sack, 1 Fum Rcvy |
| 41. | 9.00 | Week 10, 2004 | Cin | @Was@Was | 2 Tackles, 2 Assists, 1.0 Sack, 1 PD |
| 41. | 9.00 | Week 09, 2002 | Cin | @Hou@Hou | 4 Tackles, 1 Assist, 1.0 Sack |