*=Offensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 60.00 | Week 08, 2015 * | NO | NYGNYG | 511 Pass, 1 Rush, 7 TD, 1 Int |
| 2. | 50.06 | Week 14, 2019 * | NO | SFSF | 349 Pass, 1 Rush, 6 TD |
| 3. | 48.00 | Week 01, 2009 * | NO | DetDet | 358 Pass, 6 TD, 1 Int |
| 4. | 46.54 | Week 03, 2018 | NO | @Atl@Atl | 396 Pass, 7 Rush, 5 TD |
| 5. | 45.00 | Week 17, 2013 | NO | TBTB | 381 Pass, 8 Rush, 5 TD |
| 5. | 45.00 | Week 15, 2011 | NO | @Min@Min | 412 Pass, 4 Rush, 5 TD, 1 Fumb |
| 5. | 45.00 | Week 14, 2006 * | NO | @Dal@Dal | 384 Pass, - 6 Rush, 5 TD |
| 8. | 44.00 | Week 12, 2011 * | NO | NYGNYG | 363 Pass, 8 Rush, 5 TD |
| 8. | 44.00 | Week 12, 2009 * | NO | NENE | 371 Pass, - 1 Rush, 5 TD |
| 10. | 43.00 | Week 08, 2013 * | NO | BufBuf | 332 Pass, - 1 Rush, 5 TD |
| 10. | 43.00 | Week 17, 2011 | NO | CarCar | 389 Pass, 5 Rush, 5 TD, 1 Int |
| 10. | 43.00 | Week 07, 2011 * | NO | IndInd | 325 Pass, 5 TD |
| 10. | 43.00 | Week 08, 2004 | SD | OakOak | 281 Pass, 21 Rush, 5 TD |
| 14. | 41.00 | Week 12, 2016 * | NO | LALA | 310 Pass, 1 Rush, 5 TD, 1 Fumb |
| 15. | 40.00 | Week 06, 2016 | NO | CarCar | 465 Pass, 4 TD, 1 Int |
| 15. | 40.00 | Week 13, 2014 | NO | @Pit@Pit | 257 Pass, 5 TD |
| 15. | 40.00 | Week 04, 2013 * | NO | MiaMia | 413 Pass, 2 Rush, 4 TD |
| 18. | 39.44 | Week 09, 2018 * | NO | LARLAR | 346 Pass, 16 Rush, 4 TD |
| 19. | 39.00 | Week 01, 2016 | NO | OakOak | 423 Pass, 5 Rush, 4 TD, 1 Fumb |
| 19. | 39.00 | Week 10, 2013 * | NO | DalDal | 392 Pass, 4 TD |
| 21. | 38.52 | Week 11, 2018 | NO | PhiPhi | 363 Pass, 4 TD |
| 22. | 38.00 | Week 15, 2016 | NO | @Ari@Ari | 389 Pass, - 2 Rush, 4 TD, 1 Fumb |
| 22. | 38.00 | Week 06, 2009 | NO | NYGNYG | 369 Pass, 6 Rush, 4 TD |
| 24. | 37.56 | Week 01, 2018 | NO | TBTB | 439 Pass, 3 TD, 1 2-Pt |
| 25. | 37.00 | Week 09, 2015 | NO | TenTen | 387 Pass, - 1 Rush, 4 TD, 1 Int |
| 25. | 37.00 | Week 03, 2013 * | NO | AriAri | 342 Pass, 21 Rush, 4 TD, 1 Int |
| 25. | 37.00 | Week 17, 2012 | NO | CarCar | 396 Pass, 4 TD, 1 Int |
| 25. | 37.00 | Week 15, 2012 | NO | TBTB | 307 Pass, 11 Rush, 4 TD |
| 25. | 37.00 | Week 07, 2012 * | NO | @TB@TB | 377 Pass, 1 Rush, 4 TD, 1 Int |
| 25. | 37.00 | Week 17, 2008 | NO | CarCar | 386 Pass, 4 TD, 1 Int |
| 25. | 37.00 | Week 08, 2007 | NO | @SF@SF | 336 Pass, 4 TD |
| 25. | 37.00 | Week 11, 2005 * | SD | BufBuf | 339 Pass, - 1 Rush, 4 TD |
| 33. | 36.28 | Week 15, 2019 | NO | IndInd | 307 Pass, 4 TD |
| 34. | 36.00 | Week 14, 2013 | NO | CarCar | 313 Pass, 3 Rush, 4 TD |
| 34. | 36.00 | Week 05, 2012 * | NO | SDSD | 370 Pass, - 2 Rush, 4 TD, 1 Int |
| 34. | 36.00 | Week 12, 2008 | NO | GBGB | 323 Pass, 4 TD |
| 37. | 35.00 | Week 16, 2012 | NO | @Dal@Dal | 446 Pass, - 1 Rush, 3 TD |
| 37. | 35.00 | Week 04, 2012 | NO | @GB@GB | 446 Pass, 3 TD |
| 37. | 35.00 | Week 11, 2010 | NO | SeaSea | 382 Pass, 4 TD, 2 Int |
| 40. | 34.90 | Week 10, 2018 | NO | @Cin@Cin | 265 Pass, 3 Rush, 4 TD |
| 41. | 34.00 | Week 16, 2015 | NO | JacJac | 412 Pass, - 3 Rush, 3 TD |
| 41. | 34.00 | Week 01, 2011 | NO | @GB@GB | 419 Pass, 3 Rush, 3 TD |
| 41. | 34.00 | Week 09, 2007 | NO | JacJac | 445 Pass, 7 Rush, 3 TD, 1 Fumb |
| 41. | 34.00 | Week 09, 2004 | SD | NONO | 257 Pass, 4 Rush, 4 TD |
| 45. | 33.22 | Week 05, 2018 | NO | WasWas | 363 Pass, 1 Rush, 1 Receiving, 1 Rec, 3 TD |
| 46. | 33.00 | Week 15, 2014 | NO | @Chi@Chi | 375 Pass, 2 Rush, 3 TD |
| 46. | 33.00 | Week 12, 2014 | NO | BalBal | 420 Pass, 15 Rush, 3 TD, 1 Int |
| 48. | 32.00 | Week 15, 2015 | NO | DetDet | 341 Pass, 11 Rush, 3 TD |
| 48. | 32.00 | Week 16, 2011 | NO | AtlAtl | 307 Pass, 9 Rush, 4 TD, 2 Int |
| 48. | 32.00 | Week 03, 2011 | NO | HouHou | 370 Pass, - 1 Rush, 3 TD, 2 Int, 2 2-Pt |