*=Defensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 18.00 | Week 13, 2003 | SD | KCKC | 4 Tackles, 1 Assist, 2 Int3 PD |
| 2. | 17.00 | Week 13, 2008 | SD | AtlAtl | 8 Tackles, 2 FF, 1 Fum Rcvy |
| 2. | 17.00 | Week 12, 2008 | SD | IndInd | 9 Tackles, 2 Assists, 1 Int, 1 PD |
| 2. | 17.00 | Week 15, 2005 | SD | 55 | 4 Tackles, 3 Assists, 1 Int5 PD |
| 5. | 15.00 | Week 02, 2008 | SD | @Den@Den | 10 Tackles, 1 Assist, 1 FF, 1 PD |
| 5. | 15.00 | Week 15, 2006 | SD | KCKC | 10 Tackles, 5 PD |
| 5. | 15.00 | Week 11, 2003 | SD | @Den@Den | 7 Tackles, 1 Assist, 1 Int2 PD |
| 8. | 14.00 | Week 06, 2012 | SD | DenDen | 1 Tackle, 1 Assist, 1 Int, 1 TD, 1 PD |
| 8. | 14.00 | Week 12, 2009 | SD | KCKC | 4 Tackles, 1 Assist, 1 Int, 1 FF, 1 PD |
| 8. | 14.00 | Week 11, 2008 | SD | @Pit@Pit | 9 Tackles, 3 Assists, 2 PD |
| 8. | 14.00 | Week 14, 2004 | SD | TBTB | 6 Tackles, 1 Assist, 1 Int2 PD |
| 12. | 13.00 | Week 05, 2012 | SD | @NO@NO | 4 Tackles, 2 Assists, 1 Int, 2 PD |
| 12. | 13.00 | Week 15, 2009 | SD | CinCin | 4 Tackles, 2 Assists, 1 Int, 2 PD |
| 12. | 13.00 | Week 06, 2008 | SD | NENE | 3 Tackles, 1 Int, 5 PD |
| 15. | 12.00 | Week 12, 2006 | SD | OakOak | 3 Tackles, 1 Assist, 1 Int3 PD |
| 16. | 11.00 | Week 13, 2012 | SD | CinCin | 7 Tackles, 1 Assist, 1 Fum Rcvy |
| 16. | 11.00 | Week 04, 2012 | SD | @KC@KC | 8 Tackles, 1 FF |
| 16. | 11.00 | Week 16, 2007 | SD | DenDen | 4 Tackles, 1 Int, 2 PD |
| 16. | 11.00 | Week 05, 2007 | SD | @Den@Den | 6 Tackles, 1 Assist, 1 Fum Rcvy, 1 PD |
| 16. | 11.00 | Week 04, 2006 | SD | @Bal@Bal | 4 Tackles, 1 Int2 PD |
| 16. | 11.00 | Week 02, 2006 | SD | TenTen | 5 Tackles, 1 Int1 PD |
| 16. | 11.00 | Week 07, 2005 | SD | @Phi@Phi | 8 Tackles, 2 Assists, 1 PD |
| 23. | 10.00 | Week 03, 2010 | SD | @Sea@Sea | 3 Tackles, 1 Int, 2 PD |
| 23. | 10.00 | Week 02, 2007 | SD | @NE@NE | 7 Tackles, 1 Fum Rcvy |
| 23. | 10.00 | Week 14, 2005 | SD | MiaMia | 6 Tackles, 1 FF, 1 PD |
| 23. | 10.00 | Week 01, 2003 | SD | @KC@KC | 4 Tackles, 1 Int1 PD |
| 23. | 10.00 | Week 14, 2002 | SD | OakOak | 7 Tackles, 3 Assists |
| 28. | 9.00 | Week 01, 2012 | SD | @Oak@Oak | 6 Tackles, 1 Assist, 2 PD |
| 28. | 9.00 | Week 17, 2010 | SD | @Den@Den | 3 Tackles, 1 Int, 1 PD |
| 28. | 9.00 | Week 17, 2006 | SD | AriAri | 7 Tackles, 2 PD |
| 28. | 9.00 | Week 10, 2006 | SD | @Cin@Cin | 5 Tackles, 2 Assists, 2 PD |
| 28. | 9.00 | Week 16, 2005 | SD | @KC@KC | 7 Tackles, 1 Assist, 1 PD |
| 28. | 9.00 | Week 13, 2002 | SD | DenDen | 7 Tackles, 2 Assists |
| 34. | 8.00 | Week 12, 2012 | SD | BalBal | 6 Tackles, 1 Assist, 1 PD |
| 34. | 8.00 | Week 09, 2010 | SD | @Hou@Hou | 6 Tackles, 1 Assist, 1 PD |
| 34. | 8.00 | Week 04, 2009 | SD | @Pit@Pit | 5 Tackles, 3 Assists |
| 34. | 8.00 | Week 01, 2009 | SD | @Oak@Oak | 1 Int, 3 PD |
| 34. | 8.00 | Week 03, 2008 | SD | NYJNYJ | 2 Tackles, 1 Assist, 1 Fum Rcvy, 2 PD |
| 34. | 8.00 | Week 08, 2007 | SD | HouHou | 5 Tackles, 1 Assist, 2 PD |
| 34. | 8.00 | Week 16, 2006 | SD | @Sea@Sea | 5 Tackles, 2 Assists, 1 PD |
| 34. | 8.00 | Week 09, 2006 | SD | CleCle | 6 Tackles, 1 Assist, 1 PD |
| 42. | 7.00 | Week 17, 2012 | SD | OakOak | 1 Tackle, 1 Int, 1 PD |
| 42. | 7.00 | Week 09, 2012 | SD | KCKC | 3 Tackles, 1 Assist, 1 Fum Rcvy |
| 42. | 7.00 | Week 02, 2009 | SD | BalBal | |
| 42. | 7.00 | Week 10, 2008 | SD | KCKC | 3 Tackles, 1 Assist, 3 PD |
| 42. | 7.00 | Week 07, 2008 | SD | @Buf@Buf | 6 Tackles, 1 Assist |
| 42. | 7.00 | Week 01, 2008 | SD | CarCar | 4 Tackles, 2 Assists, 1 PD |
| 42. | 7.00 | Week 13, 2006 | SD | @Buf@Buf | 1 Tackle, 1 Int1 PD |
| 42. | 7.00 | Week 05, 2006 | SD | PitPit | 7 Tackles |
| 42. | 7.00 | Week 09, 2005 | SD | @NYJ@NYJ | 3 Tackles, 2 Assists, 2 PD |