*=Offensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 46.00 | Week 14, 2013 * | Chi | DalDal | 348 Pass, 16 Rush, 5 TD, 1 2-Pt |
| 2. | 37.00 | Week 05, 2015 * | Cle | @Bal@Bal | 457 Pass, 12 Rush, 3 TD |
| 2. | 37.00 | Week 15, 2004 | Ari | StLStL | 287 Pass, 33 Rush, 4 TD, 1 Fumb |
| 4. | 32.00 | Week 13, 2017 | NYJ | KCKC | 331 Pass, 19 Rush, 3 TD |
| 5. | 31.00 | Week 12, 2017 | NYJ | CarCar | 307 Pass, 28 Rush, 3 TD, 1 Fumb |
| 6. | 30.00 | Week 07, 2017 | NYJ | @Mia@Mia | 209 Pass, 1 Rush, 4 TD, 1 Int |
| 7. | 29.00 | Week 04, 2005 | Ari | SFSF | 385 Pass, 32 Rush, 2 TD, 1 Fumb |
| 8. | 26.00 | Week 13, 2013 | Chi | @Min@Min | 355 Pass, 2 TD |
| 8. | 26.00 | Week 05, 2004 | Ari | @SF@SF | 231 Pass, 11 Rush, 3 TD, 1 Int |
| 10. | 25.00 | Week 04, 2015 | Cle | @SD@SD | 356 Pass, 2 TD, 1 Fumb |
| 11. | 24.00 | Week 06, 2017 | NYJ | NENE | 354 Pass, 21 Rush, 2 TD, 2 Int |
| 11. | 24.00 | Week 08, 2016 | Cle | NYJNYJ | 341 Pass, 10 Rush, 2 TD, 2 Int, 1 2-Pt |
| 11. | 24.00 | Week 08, 2015 | Cle | AriAri | 211 Pass, 18 Rush, 3 TD, 1 Int, 1 Fumb |
| 11. | 24.00 | Week 09, 2013 | Chi | @GB@GB | 272 Pass, 20 Rush, 2 TD |
| 11. | 24.00 | Week 13, 2007 | Oak | DenDen | 141 Pass, 22 Rush, 3 TD, 1 Fumb |
| 11. | 24.00 | Week 16, 2004 | Ari | @Sea@Sea | 248 Pass, 10 Rush, 3 TD, 2 Int |
| 17. | 23.00 | Week 03, 2015 | Cle | OakOak | 341 Pass, 2 TD, 1 Int |
| 17. | 23.00 | Week 11, 2014 | TB | @Was@Was | 288 Pass, 8 Rush, 2 TD |
| 17. | 23.00 | Week 10, 2014 | TB | AtlAtl | 301 Pass, 39 Rush, 2 TD, 2 Int |
| 17. | 23.00 | Week 12, 2013 | Chi | @StL@StL | 352 Pass, 4 Rush, 2 TD, 1 Int, 1 Fumb |
| 17. | 23.00 | Week 05, 2005 | Ari | CarCar | 394 Pass, 29 Rush, 2 TD, 3 Int |
| 22. | 22.00 | Week 08, 2017 | NYJ | AtlAtl | 257 Pass, 2 TD |
| 23. | 21.00 | Week 16, 2005 | Ari | PhiPhi | 294 Pass, 8 Rush, 2 TD, 1 Int |
| 24. | 20.00 | Week 02, 2017 | NYJ | @Oak@Oak | 166 Pass, 31 Rush, 2 TD, 1 Fumb |
| 24. | 20.00 | Week 01, 2007 | Oak | DetDet | 313 Pass, 3 Rush, 2 TD, 2 Int |
| 24. | 20.00 | Week 17, 2003 | Ari | MinMin | 224 Pass, 27 Rush, 2 TD, 1 Int |
| 27. | 18.00 | Week 09, 2017 | NYJ | BufBuf | 140 Pass, 13 Rush, 2 TD |
| 27. | 18.00 | Week 02, 2016 | Cle | BalBal | 260 Pass, 2 TD, 2 Int |
| 27. | 18.00 | Week 17, 2005 | Ari | @Ind@Ind | 297 Pass, 42 Rush, 1 TD, 1 Int, 1 Fumb |
| 27. | 18.00 | Week 16, 2003 | Ari | @Sea@Sea | 274 Pass, 38 Rush, 1 TD, 1 Fumb |
| 31. | 17.54 | Week 12, 2018 | NYJ | NENE | 276 Pass, 25 Rush, 1 TD, 1 Int |
| 32. | 17.00 | Week 05, 2017 | NYJ | @Cle@Cle | 194 Pass, - 3 Rush, 2 TD, 1 Int |
| 32. | 17.00 | Week 14, 2014 | TB | @Det@Det | 250 Pass, 8 Rush, 2 TD, 2 Int, 1 Fumb |
| 32. | 17.00 | Week 02, 2014 | TB | StLStL | 179 Pass, 6 Rush, 2 TD, 1 Int |
| 32. | 17.00 | Week 01, 2014 | TB | CARCAR | 183 Pass, 27 Rush, 2 TD, 2 Int |
| 32. | 17.00 | Week 07, 2013 | Chi | @Was@Was | 204 Pass, 33 Rush, 1 TD |
| 37. | 16.00 | Week 12, 2016 | Cle | NYGNYG | 322 Pass, 1 TD, 2 Fumb |
| 37. | 16.00 | Week 06, 2015 | Cle | DenDen | 213 Pass, 12 Rush, 2 TD, 2 Int, 1 Fumb |
| 37. | 16.00 | Week 15, 2014 | TB | @Car@Car | 154 Pass, 21 Rush, 2 TD, 1 Int, 2 Fumb |
| 37. | 16.00 | Week 16, 2011 | Chi | @GB@GB | 242 Pass, 38 Rush, 1 TD, 2 Int, 1 2-Pt |
| 37. | 16.00 | Week 14, 2003 | Ari | @SF@SF | 120 Pass, 2 Rush, 2 TD |
| 42. | 15.00 | Week 03, 2017 | NYJ | MiaMia | 249 Pass, 7 Rush, 1 TD |
| 42. | 15.00 | Week 12, 2015 | Cle | BalBal | 212 Pass, 12 Rush, 1 TD |
| 42. | 15.00 | Week 12, 2014 | TB | @Chi@Chi | 341 Pass, 12 Rush, 1 TD, 2 Int, 1 Fumb |
| 45. | 14.00 | Week 10, 2017 | NYJ | @TB@TB | 262 Pass, 1 TD, 1 Int |
| 45. | 14.00 | Week 11, 2013 | Chi | BalBal | 216 Pass, - 1 Rush, 1 TD |
| 45. | 14.00 | Week 15, 2003 | Ari | CarCar | 172 Pass, 47 Rush, 1 TD, 1 Int |
| 48. | 13.00 | Week 17, 2011 | Chi | @Min@Min | 160 Pass, 30 Rush, 1 TD, 1 Int |
| 49. | 12.00 | Week 14, 2004 | Ari | SFSF | 307 Pass, 7 Rush, 1 Int, 1 2-Pt |
| 49. | 12.00 | Week 09, 2004 | Ari | @Mia@Mia | 162 Pass, 9 Rush, 1 TD |