*=Offensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 27.00 | Week 05, 2010 | Det | StLStL | 227 Pass, 9 Rush, 3 TD |
| 2. | 26.00 | Week 04, 2010 | Det | @GB@GB | 331 Pass, 53 Rush, 2 TD, 2 Int |
| 2. | 26.00 | Week 11, 2008 | SF | StLStL | 213 Pass, 5 Rush, 3 TD |
| 4. | 25.00 | Week 13, 2014 | StL | OakOak | 183 Pass, 1 Rush, 3 TD |
| 5. | 22.00 | Week 12, 2008 | SF | @Dal@Dal | 303 Pass, 2 TD, 1 Int |
| 6. | 21.00 | Week 16, 2014 | StL | NYGNYG | 290 Pass, 2 TD, 1 Int |
| 6. | 21.00 | Week 16, 2010 | Det | @Mia@Mia | 222 Pass, 10 Rush, 2 TD |
| 6. | 21.00 | Week 11, 2010 | Det | @Dal@Dal | 289 Pass, 2 TD, 1 Int |
| 6. | 21.00 | Week 14, 2008 | SF | NYJNYJ | 285 Pass, 8 Rush, 2 TD, 1 Int |
| 10. | 20.00 | Week 14, 2014 | StL | @Was@Was | 213 Pass, - 1 Rush, 2 TD |
| 10. | 20.00 | Week 16, 2007 | SF | TBTB | 123 Pass, - 1 Rush, 3 TD, 1 Int |
| 10. | 20.00 | Week 15, 2007 | SF | CinCin | 197 Pass, 12 Rush, 2 TD |
| 13. | 19.00 | Week 17, 2008 | SF | WasWas | 245 Pass, 8 Rush, 2 TD, 1 Int |
| 14. | 18.00 | Week 03, 2012 | Det | @Ten@Ten | 172 Pass, - 1 Rush, 2 TD |
| 14. | 18.00 | Week 04, 2009 | SF | StLStL | 152 Pass, - 2 Rush, 2 TD |
| 14. | 18.00 | Week 16, 2008 | SF | @StL@StL | 216 Pass, 45 Rush, 2 TD, 3 Int |
| 17. | 17.00 | Week 03, 2009 | SF | @Min@Min | 195 Pass, 2 TD, 1 Int |
| 18. | 16.00 | Week 10, 2010 | Det | @Buf@Buf | 323 Pass, 1 Rush, 1 TD, 1 Int |
| 18. | 16.00 | Week 10, 2008 | SF | @Ari@Ari | 217 Pass, 12 Rush, 2 TD, 2 Int, 1 Fumb |
| 20. | 15.00 | Week 17, 2010 | Det | MinMin | 258 Pass, 11 Rush, 1 TD, 1 Int |
| 20. | 15.00 | Week 12, 2010 | Det | NENE | 285 Pass, 23 Rush, 1 TD, 2 Int |
| 22. | 14.00 | Week 11, 2014 | StL | DenDen | 220 Pass, 1 TD |
| 22. | 14.00 | Week 08, 2008 | SF | SeaSea | 173 Pass, 20 Rush, 1 TD |
| 24. | 13.00 | Week 01, 2009 | SF | @Ari@Ari | 209 Pass, 1 TD, 1 Fumb |
| 25. | 12.00 | Week 13, 2008 | SF | @Buf@Buf | 161 Pass, 1 TD |
| 26. | 11.00 | Week 03, 2010 | Det | @Min@Min | 237 Pass, 4 Rush, 1 TD, 2 Int |
| 27. | 10.00 | Week 05, 2009 | SF | AtlAtl | 198 Pass, 53 Rush, 1 Int |
| 27. | 10.00 | Week 15, 2008 | SF | @Mia@Mia | 233 Pass, 17 Rush |
| 27. | 10.00 | Week 14, 2007 | SF | MinMin | 180 Pass, 3 Rush, 1 TD, 1 Int, 1 Fumb |
| 30. | 9.00 | Week 01, 2016 | Min | @Ten@Ten | 236 Pass, 8 Rush |
| 30. | 9.00 | Week 06, 2010 | Det | @NYG@NYG | 91 Pass, 1 TD |
| 32. | 8.00 | Week 15, 2014 | StL | AriAri | 229 Pass, 11 Rush, 1 Int |
| 32. | 8.00 | Week 12, 2014 | StL | @SD@SD | 198 Pass, 1 TD, 2 Int, 1 Fumb |
| 34. | 6.00 | Week 02, 2009 | SF | SeaSea | |
| 35. | 5.00 | Week 17, 2014 | StL | @Sea@Sea | 243 Pass, 2 Int |
| 36. | 1.00 | Week 01, 2014 | StL | MINMIN | 81 Pass, - 1 Rush, 1 Int |
| 36. | 1.00 | Week 02, 2011 | Det | KCKC | 28 Pass |
| 36. | 1.00 | Week 07, 2009 | SF | @Hou@Hou | 45 Pass, 2 Rush |
| 39. | 0.00 | Week 03, 2017 | Min | TBTB | Played, No Stats |
| 39. | 0.00 | Week 02, 2017 | Min | @Pit@Pit | Played, No Stats |
| 39. | 0.00 | Week 01, 2017 | Min | NONO | Played, No Stats |
| 39. | 0.00 | Week 17, 2016 | Min | ChiChi | - 3 Rush |
| 39. | 0.00 | Week 13, 2016 | Min | DalDal | 6 Pass |
| 39. | 0.00 | Week 03, 2016 | Min | @Car@Car | Played, No Stats |
| 39. | 0.00 | Week 16, 2015 | Min | NYGNYG | - 4 Rush |
| 39. | 0.00 | Week 11, 2015 | Min | GBGB | Played, No Stats |
| 39. | 0.00 | Week 09, 2015 | Min | StlStl | 15 Pass, - 1 Rush |
| 39. | 0.00 | Week 09, 2014 | StL | @SF@SF | Played, No Stats |
| 39. | 0.00 | Week 13, 2013 | Det | GBGB | - 2 Rush |
| 39. | 0.00 | Week 05, 2013 | Det | @GB@GB | Played, No Stats |