*=Defensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 18.00 | Week 16, 2011 | Buf | DenDen | 6 Tackles, 3 Assists, 2.0 Sacks, 1 PD |
| 2. | 14.00 | Week 15, 2011 | Buf | MiaMia | 5 Tackles, 2 Assists, 1.0 Sack, 1 FF |
| 2. | 14.00 | Week 05, 2007 | Buf | DalDal | 2 Tackles, 1 Int, 1 TD, 1 PD |
| 4. | 13.00 | Week 06, 2012 | Buf | @Ari@Ari | 6 Tackles, 1 Assist, 1.0 Sack, 1 Safety |
| 4. | 13.00 | Week 12, 2010 | Buf | PitPit | 5 Tackles, 4 Assists, 1.0 Sack |
| 6. | 12.00 | Week 06, 2009 | Buf | @NYJ@NYJ | 6 Tackles, 6 Assists |
| 6. | 12.00 | Week 03, 2009 | Buf | NONO | 6 Tackles, 2 Assists, 1.0 Sack |
| 6. | 12.00 | Week 15, 2004 | Buf | @Cin@Cin | 5 Tackles, 1 Assist, 1 Int1 PD |
| 9. | 11.00 | Week 13, 2008 | Buf | SFSF | 5 Tackles, 2 Assists, 1.0 Sack |
| 9. | 11.00 | Week 01, 2006 | Buf | @NE@NE | 4 Tackles, 1.0 Sack, 1 FF |
| 9. | 11.00 | Week 01, 2005 | Buf | HouHou | 2 Tackles, 2 Assists, 1.0 Sack, 1 FF |
| 12. | 10.00 | Week 14, 2009 | Buf | @KC@KC | 2 Tackles, 1 Assist, 1.0 Sack, 1 FF |
| 12. | 10.00 | Week 03, 2008 | Buf | OakOak | 2 Tackles, 1.0 Sack, 1 FF, 1 PD |
| 12. | 10.00 | Week 10, 2007 | Buf | @Mia@Mia | 4 Tackles, 1.0 Sack, 1 Safety |
| 12. | 10.00 | Week 06, 2006 | Buf | @Det@Det | 3 Tackles, 3 Assists, 1.0 Sack |
| 16. | 9.00 | Week 17, 2010 | Buf | @NYJ@NYJ | 7 Tackles, 2 Assists |
| 16. | 9.00 | Week 13, 2009 | Buf | NYJNYJ | 3 Tackles, 2 Assists, 1.0 Sack |
| 16. | 9.00 | Week 08, 2009 | Buf | HouHou | 4 Tackles, 3 Assists, 0.5 Sack |
| 16. | 9.00 | Week 07, 2006 | Buf | NENE | 4 Tackles, 1 Assist, 1.0 Sack |
| 16. | 9.00 | Week 14, 2004 | Buf | CleCle | 2 Tackles, 1.0 Sack, 1 Fum Rcvy |
| 16. | 9.00 | Week 09, 2004 | Buf | NYJNYJ | 3 Tackles, 2 Assists, 1.0 Sack |
| 22. | 8.00 | Week 16, 2010 | Buf | NENE | 1 Tackle, 2 Assists, 1.0 Sack, 1 PD |
| 22. | 8.00 | Week 07, 2010 | Buf | @Bal@Bal | 2 Tackles, 1 Assist, 1.0 Sack, 1 PD |
| 22. | 8.00 | Week 02, 2010 | Buf | @GB@GB | 7 Tackles, 1 Assist |
| 22. | 8.00 | Week 07, 2009 | Buf | @Car@Car | 4 Tackles, 1.0 Sack |
| 22. | 8.00 | Week 03, 2007 | Buf | @NE@NE | 5 Tackles, 3 Assists |
| 22. | 8.00 | Week 04, 2004 | Buf | NENE | 1 Tackle, 1 Assist, 1 FF, 1 Fum Rcvy |
| 28. | 7.00 | Week 14, 2010 | Buf | CleCle | 4 Tackles, 1 FF |
| 28. | 7.00 | Week 11, 2010 | Buf | @Cin@Cin | 2 Tackles, 1.0 Sack, 1 PD |
| 28. | 7.00 | Week 01, 2010 | Buf | MiaMia | 3 Tackles, 4 Assists |
| 28. | 7.00 | Week 17, 2009 | Buf | IndInd | 3 Tackles, 1 Assist, 1 Fum Rcvy |
| 28. | 7.00 | Week 17, 2008 | Buf | NENE | 5 Tackles, 2 Assists |
| 28. | 7.00 | Week 10, 2008 | Buf | @NE@NE | 4 Tackles, 3 Assists |
| 28. | 7.00 | Week 17, 2007 | Buf | @Phi@Phi | 3 Tackles, 1 Assist, 0.5 Sack, 1 PD |
| 28. | 7.00 | Week 02, 2006 | Buf | @Mia@Mia | 2 Tackles, 1 Assist, 1.0 Sack |
| 28. | 7.00 | Week 10, 2004 | Buf | @NE@NE | 2 Tackles, 1 Assist, 1.0 Sack |
| 37. | 6.00 | Week 07, 2012 | Buf | TenTen | 2 Tackles, 1.0 Sack |
| 37. | 6.00 | Week 14, 2011 | Buf | @SD@SD | 3 Tackles, 3 Assists |
| 37. | 6.00 | Week 10, 2010 | Buf | DetDet | 4 Tackles, 2 Assists |
| 37. | 6.00 | Week 05, 2010 | Buf | JacJac | 2 Tackles, 4 Assists |
| 37. | 6.00 | Week 15, 2009 | Buf | NENE | 3 Tackles, 3 Assists |
| 37. | 6.00 | Week 04, 2009 | Buf | @Mia@Mia | 1 Tackle, 1 Assist, 1.0 Sack |
| 37. | 6.00 | Week 04, 2007 | Buf | NYJNYJ | 2 Tackles, 1.0 Sack |
| 37. | 6.00 | Week 13, 2006 | Buf | SDSD | 3 Tackles, 1 Fum Rcvy |
| 37. | 6.00 | Week 05, 2006 | Buf | @Chi@Chi | 4 Tackles, 2 Assists |
| 37. | 6.00 | Week 03, 2006 | Buf | NYJNYJ | 1 Tackle, 1 Assist, 1.0 Sack |
| 37. | 6.00 | Week 13, 2005 | Buf | @Mia@Mia | 3 Tackles, 2 Assists, 1 PD |
| 37. | 6.00 | Week 05, 2005 | Buf | MiaMia | 1 Tackle, 1 Assist, 1.0 Sack |
| 37. | 6.00 | Week 03, 2005 | Buf | AtlAtl | 1 Int1 PD |
| 37. | 6.00 | Week 05, 2004 | Buf | @NYJ@NYJ | 1 Tackle, 1 Assist, 1.0 Sack |