*=Defensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 11.00 | Week 04, 2008 | SD | @Oak@Oak | 3 Tackles, 2 Assists, 1.5 Sacks |
| 1. | 11.00 | Week 06, 2006 | SD | @SF@SF | 1 Tackle, 1.0 Sack, 1 Int1 PD |
| 1. | 11.00 | Week 11, 2005 | SD | BufBuf | 4 Tackles, 1.0 Sack, 1 FF |
| 1. | 11.00 | Week 08, 2005 | SD | KCKC | 3 Tackles, 2 Assists, 1.5 Sacks |
| 5. | 10.00 | Week 06, 2007 | SD | OakOak | 5 Tackles, 1 Assist, 1.0 Sack |
| 5. | 10.00 | Week 05, 2006 | SD | PitPit | 1 Tackle, 3 Assists, 1.5 Sacks |
| 5. | 10.00 | Week 01, 2006 | SD | @Oak@Oak | 2 Tackles, 2 Assists, 1.5 Sacks |
| 8. | 9.00 | Week 14, 2006 | SD | DenDen | 4 Tackles, 1 Assist, 1.0 Sack |
| 8. | 9.00 | Week 15, 2005 | SD | 00 | 5 Tackles, 1.0 Sack |
| 10. | 8.00 | Week 16, 2008 | SD | @TB@TB | 3 Tackles, 2 Assists, 1 FF |
| 10. | 8.00 | Week 16, 2005 | SD | @KC@KC | 6 Tackles, 2 Assists |
| 12. | 7.00 | Week 14, 2010 | SD | KCKC | 1 Tackle, 2 Assists, 1.0 Sack |
| 12. | 7.00 | Week 17, 2008 | SD | DenDen | 1 Assist, 1 Int, 1 PD |
| 12. | 7.00 | Week 16, 2007 | SD | DenDen | 2 Tackles, 1.0 Sack, 1 PD |
| 12. | 7.00 | Week 09, 2007 | SD | @Min@Min | 3 Tackles, 1.0 Sack |
| 12. | 7.00 | Week 04, 2007 | SD | KCKC | 4 Tackles, 3 Assists |
| 12. | 7.00 | Week 15, 2006 | SD | KCKC | 3 Tackles, 1.0 Sack |
| 12. | 7.00 | Week 09, 2006 | SD | CleCle | 2 Tackles, 1 Assist, 1.0 Sack |
| 12. | 7.00 | Week 07, 2006 | SD | @KC@KC | 3 Tackles, 1 Assist, 1 Fum Rcvy |
| 20. | 6.00 | Week 04, 2009 | SD | @Pit@Pit | 4 Tackles, 2 Assists |
| 20. | 6.00 | Week 02, 2009 | SD | BalBal | |
| 20. | 6.00 | Week 08, 2006 | SD | StLStL | 5 Tackles, 1 Assist |
| 23. | 5.00 | Week 15, 2010 | SD | SFSF | 1 Tackle, 1.0 Sack |
| 23. | 5.00 | Week 06, 2010 | SD | @StL@StL | 3 Tackles, 0.5 Sack |
| 23. | 5.00 | Week 07, 2008 | SD | @Buf@Buf | 1 Tackle, 4 Assists |
| 23. | 5.00 | Week 06, 2008 | SD | NENE | 5 Tackles |
| 23. | 5.00 | Week 01, 2007 | SD | ChiChi | 3 Tackles, 2 Assists |
| 23. | 5.00 | Week 02, 2006 | SD | TenTen | 4 Tackles, 1 Assist |
| 23. | 5.00 | Week 17, 2005 | SD | DenDen | 4 Tackles, 1 PD |
| 30. | 4.00 | Week 13, 2010 | SD | OakOak | 3 Tackles, 1 Assist |
| 30. | 4.00 | Week 03, 2009 | SD | MiaMia | 3 Tackles, 1 Assist |
| 30. | 4.00 | Week 01, 2008 | SD | CarCar | 3 Tackles, 1 Assist |
| 30. | 4.00 | Week 08, 2007 | SD | HouHou | 1 Tackle, 1 Assist, 0.5 Sack |
| 30. | 4.00 | Week 14, 2005 | SD | MiaMia | 4 Tackles |
| 30. | 4.00 | Week 05, 2005 | SD | PitPit | 4 Assists |
| 36. | 3.00 | Week 16, 2010 | SD | @Cin@Cin | 2 Tackles, 1 Assist |
| 36. | 3.00 | Week 04, 2010 | SD | AriAri | 1 Fum Rcvy |
| 36. | 3.00 | Week 16, 2009 | SD | @Ten@Ten | 3 Tackles |
| 36. | 3.00 | Week 13, 2008 | SD | AtlAtl | 3 Tackles |
| 36. | 3.00 | Week 17, 2007 | SD | @Oak@Oak | 3 Tackles |
| 36. | 3.00 | Week 02, 2007 | SD | @NE@NE | 2 Tackles, 1 Assist |
| 36. | 3.00 | Week 04, 2006 | SD | @Bal@Bal | 3 Tackles |
| 36. | 3.00 | Week 12, 2005 | SD | @Was@Was | 3 Tackles |
| 36. | 3.00 | Week 04, 2005 | SD | @NE@NE | 1 Tackle, 2 Assists |
| 45. | 2.00 | Week 17, 2010 | SD | @Den@Den | 2 Tackles |
| 45. | 2.00 | Week 12, 2010 | SD | @Ind@Ind | 2 Tackles |
| 45. | 2.00 | Week 09, 2010 | SD | @Hou@Hou | 2 Tackles |
| 45. | 2.00 | Week 05, 2010 | SD | @Oak@Oak | 1 Tackle, 1 Assist |
| 45. | 2.00 | Week 03, 2010 | SD | @Sea@Sea | 1 Tackle, 1 Assist |
| 45. | 2.00 | Week 14, 2009 | SD | @Dal@Dal | 1 Tackle, 1 Assist |