*=Defensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 20.00 | Week 11, 2013 | Buf | NYJNYJ | 3 Tackles, 1 Assist, 1.0 Sack, 2 Int, 2 PD |
| 2. | 19.00 | Week 16, 2011 | Buf | DenDen | 5 Tackles, 2 Assists, 1 Int, 1 TD, 1 PD |
| 3. | 18.00 | Week 16, 2016 | NO | TBTB | 3 Tackles, 3 Assists, 2 Int, 2 PD |
| 3. | 18.00 | Week 04, 2012 | Buf | NENE | 5 Tackles, 4 Assists, 2 FF, 1 Fum Rcvy |
| 3. | 18.00 | Week 17, 2010 | Buf | @NYJ@NYJ | 4 Tackles, 2 Assists, 1 Int, 1 TD, 1 PD |
| 6. | 17.00 | Week 12, 2010 | Buf | PitPit | 7 Tackles, 4 Assists, 1 FF, 1 Fum Rcvy |
| 6. | 17.00 | Week 08, 2009 | Buf | HouHou | 2 Tackles, 3 Assists, 2 Int, 2 PD |
| 8. | 16.00 | Week 06, 2012 | Buf | @Ari@Ari | 4 Tackles, 2 Int, 2 PD |
| 8. | 16.00 | Week 06, 2009 | Buf | @NYJ@NYJ | 2 Tackles, 1 Assist, 2 Int, 3 PD |
| 10. | 15.00 | Week 05, 2011 | Buf | PhiPhi | 8 Tackles, 1 FF, 1 Fum Rcvy, 1 PD |
| 11. | 14.00 | Week 11, 2012 | Buf | MiaMia | 2 Tackles, 2 Assists, 1 Int, 1 Fum Rcvy, 2 PD |
| 11. | 14.00 | Week 08, 2011 | Buf | WasWas | 3 Tackles, 1 Assist, 1.0 Sack, 1 Int, 1 PD |
| 11. | 14.00 | Week 03, 2011 | Buf | NENE | 8 Tackles, 4 Assists, 2 PD |
| 11. | 14.00 | Week 14, 2010 | Buf | CleCle | 6 Tackles, 2 Assists, 2 FF |
| 11. | 14.00 | Week 07, 2009 | Buf | @Car@Car | 2 Tackles, 2 Int, 2 PD |
| 16. | 13.00 | Week 12, 2015 | NO | @Hou@Hou | 4 Tackles, 3 Assists, 1 Int, 1 PD |
| 16. | 13.00 | Week 02, 2012 | Buf | KCKC | 4 Tackles, 3 Assists, 1 Int, 1 PD |
| 16. | 13.00 | Week 05, 2009 | Buf | CleCle | 4 Tackles, 3 Assists, 1 Int, 1 PD |
| 19. | 12.00 | Week 13, 2011 | Buf | TenTen | 8 Tackles, 1 Assist, 1 FF |
| 19. | 12.00 | Week 09, 2011 | Buf | NYJNYJ | 3 Tackles, 3 Assists, 1 Int, 1 PD |
| 21. | 11.00 | Week 10, 2013 | Buf | @Pit@Pit | 4 Tackles, 1 Assist, 1 Int, 1 PD |
| 21. | 11.00 | Week 10, 2011 | Buf | @Dal@Dal | 6 Tackles, 2 Assists, 1 FF |
| 23. | 10.00 | Week 13, 2016 | NO | DetDet | 7 Tackles, 2 Assists, 1 PD |
| 23. | 10.00 | Week 08, 2016 | NO | SeaSea | 8 Tackles, 2 Assists |
| 23. | 10.00 | Week 10, 2015 | NO | @Was@Was | 3 Tackles, 3 Assists, 1.0 Sack |
| 23. | 10.00 | Week 09, 2015 | NO | TenTen | 7 Tackles, 3 Assists |
| 23. | 10.00 | Week 14, 2013 | Buf | @TB@TB | 3 Tackles, 1 Assist, 1 Int, 1 PD |
| 23. | 10.00 | Week 02, 2011 | Buf | OakOak | 8 Tackles, 2 Assists |
| 23. | 10.00 | Week 09, 2010 | Buf | ChiChi | 6 Tackles, 4 Assists |
| 23. | 10.00 | Week 03, 2010 | Buf | @NE@NE | 5 Tackles, 2 Assists, 1 Fum Rcvy |
| 23. | 10.00 | Week 14, 2009 | Buf | @KC@KC | 3 Tackles, 1 Assist, 1 Int, 1 PD |
| 32. | 9.00 | Week 08, 2015 | NO | NYGNYG | 2 Tackles, 1 Assist, 1 FF, 1 Fum Rcvy |
| 32. | 9.00 | Week 13, 2013 | Buf | AtlAtl | 6 Tackles, 3 Assists |
| 32. | 9.00 | Week 07, 2012 | Buf | TenTen | 4 Tackles, 2 Assists, 1 FF |
| 35. | 8.00 | Week 09, 2016 | NO | @SF@SF | 7 Tackles, 1 Assist |
| 35. | 8.00 | Week 04, 2014 | NO | @Dal@Dal | 6 Tackles, 1 Assist, 1 PD |
| 35. | 8.00 | Week 01, 2014 | NO | @ATL@ATL | 5 Tackles, 1 FF |
| 35. | 8.00 | Week 16, 2010 | Buf | NENE | 6 Tackles, 2 Assists |
| 35. | 8.00 | Week 15, 2010 | Buf | @Mia@Mia | 4 Tackles, 1.0 Sack |
| 35. | 8.00 | Week 04, 2010 | Buf | NYJNYJ | 4 Tackles, 4 Assists |
| 35. | 8.00 | Week 10, 2009 | Buf | @Ten@Ten | 1 Tackle, 1 Assist, 1 Int, 1 PD |
| 42. | 7.00 | Week 14, 2016 | NO | @TB@TB | 1 Tackle, 6 Assists |
| 42. | 7.00 | Week 02, 2016 | NO | @NYG@NYG | 5 Tackles, 2 Assists |
| 42. | 7.00 | Week 16, 2012 | Buf | @Mia@Mia | 4 Tackles, 1 FF |
| 42. | 7.00 | Week 13, 2012 | Buf | JacJac | 1 Tackle, 1 Int, 1 PD |
| 42. | 7.00 | Week 04, 2011 | Buf | @Cin@Cin | 5 Tackles, 2 Assists |
| 42. | 7.00 | Week 10, 2010 | Buf | DetDet | 4 Tackles, 2 Assists, 1 PD |
| 48. | 6.00 | Week 03, 2016 | NO | AtlAtl | 4 Tackles, 2 Assists |
| 48. | 6.00 | Week 14, 2015 | NO | @TB@TB | 4 Tackles, 1 Assist, 1 PD |
| 48. | 6.00 | Week 03, 2014 | NO | MinMin | 5 Tackles, 1 Assist |