| Pos. | Starters | Proteam | TW | PPG | Total | Breakdown |
| QB | Lamar Jackson | Bal | 37.64 | 22.44 | 291.76 | 316 Pass, 70 Rush, 3 TD, 1 Int, 1 2-Pt |
| RB | Austin Ekeler | LAC | 18.50 | 13.51 | 135.10 | 51 Rush, 49 Receiving, 5 Rec, 1 TD |
| RB | Raheem Mostert | Mia | 22.50 | 17.49 | 227.40 | 96 Rush, 4 Receiving, 1 Rec, 2 TD |
| WR | DeAndre Hopkins | Ten | 21.90 | 11.94 | 155.20 | 124 Receiving, 7 Rec, 1 TD |
| WR | CeeDee Lamb | Dal | 16.10 | 18.21 | 236.70 | 71 Receiving, 6 Rec, 1 TD |
| WR | Jaylen Waddle | Mia | 10.90 | 11.06 | 132.70 | 79 Receiving, 6 Rec |
| TE | Jonnu Smith | Atl | 4.70 | 5.96 | 77.50 | 27 Receiving, 4 Rec |
| HB | Tony Pollard | Dal | 13.10 | 12.58 | 163.60 | 59 Rush, 37 Receiving, 7 Rec |
| PK | Dustin Hopkins | Cle | 9.00 | 10.54 | 137.00 | 1 FG(50-59), 4 XP |
| DL | Denico Autry | Ten | 2.00 | 6.38 | 83.00 | 2 Tackles |
| DL | Quinnen Williams | NYJ | 7.00 | 6.00 | 78.00 | 2 Tackles, 1 Assist, 1.0 Sack |
| DL | Jonathon Cooper | Den | 8.00 | 8.00 | 104.00 | 2 Tackles, 1 Int, 1 PD |
| LB | Jack Gibbens | Ten | 6.00 | 7.31 | 95.00 | 3 Tackles, 3 Assists |
| LB | Ja'Whaun Bentley | NE | 7.00 | 9.00 | 108.00 | 2 Tackles, 5 Assists |
| LB | Elandon Roberts | Pit | 11.00 | 7.46 | 97.00 | 2 Tackles, 4 Assists, 1.0 Sack, 1 PD |
| CB | Kenny Moore | Ind | 4.00 | 9.23 | 120.00 | 3 Tackles, 1 PD |
| S | Josh Metellus | Min | 10.00 | 9.00 | 117.00 | 4 Tackles, 3 Assists, 1 FF |
| Pos. | 1st Backup | Proteam | TW | PPG | Total | Breakdown |
| QB | Geno Smith | Sea | DNP | 17.01 | 204.10 | Did Not Play |
| RB | Tyjae Spears | Ten | 0(14.80) | 6.88 | 89.40 | 29 Rush, 89 Receiving, 6 Rec |
| WR | Tyler Boyd | Cin | 0(3.30) | 7.06 | 91.80 | 23 Receiving, 2 Rec |
| TE | Donald Parham | LAC | 0(1.60) | 4.24 | 55.10 | 11 Receiving, 1 Rec |
| WR | Quentin Johnston | LAC | 0(10.60) | 4.15 | 54.00 | 91 Receiving, 3 Rec |
| PK | Nicholas Folk | Ten | 0(8.00) | 8.54 | 111.00 | 2 FG(<40), 2 XP |
| DL | Justin Madubuike | Bal | 0(11.00) | 7.00 | 91.00 | 5 Tackles, 2 Assists, 1.0 Sack |
| LB | Alex Anzalone | Det | 0(9.00) | 9.58 | 115.00 | 5 Tackles, 4 Assists |
| CB | Trent McDuffie | KC | 0(11.00) | 7.77 | 101.00 | 3 Tackles, 3 Assists, 1.0 Sack, 1 PD |
| S | Harrison Smith | Min | 0(2.00) | 7.46 | 97.00 | 1 Tackle, 1 Assist |
| Pos. | 2nd Backup | Proteam | TW | PPG | Total | Breakdown |
| QB | Jake Browning | Cin | 0(27.70) | 11.78 | 82.46 | 275 Pass, 7 Rush, 3 TD, 1 Int |
| RB | Khalil Herbert | Chi | 0(0.80) | 7.28 | 58.20 | 8 Rush |
| WR | Michael Gallup | Dal | 0(12.30) | 5.23 | 68.00 | 48 Receiving, 3 Rec, 1 TD |
| TE | Dalton Schultz | Hou | DNP | 8.59 | 94.50 | Did Not Play |
| RB | Jordan Mason | SF | 0(9.10) | 2.74 | 35.60 | 20 Rush, 6 Receiving, 1 Rec, 1 TD |
| Offense = 154.34 Defense = 55 Total = 209.34 | ||||||
| Pos. | Bench | Proteam | TW | PPG | Total | Breakdown |
| LB | Drue Tranquill | KC | DNP | 7.67 | 92.00 | Did Not Play |