| Pos. | Starters | Proteam | TW | PPG | Total | Breakdown |
| QB | Josh Allen | Buf | 20.90 | 28.11 | 449.72 | 120 Pass, 81 Rush, 2 TD, 3 Int, 1 2-Pt |
| RB | Dalvin Cook | Min | 2.80 | 15.22 | 182.60 | 13 Rush, 3 Rec |
| RB | David Montgomery | Chi | 19.10 | 13.84 | 166.10 | 64 Rush, 17 Receiving, 2 Rec, 2 TD, 1 Int |
| WR | Tyreek Hill | KC | 7.20 | 15.08 | 241.30 | 2 Rush, 40 Receiving, 6 Rec |
| WR | Darnell Mooney | Chi | 16.40 | 10.04 | 160.60 | 69 Receiving, 7 Rec, 1 TD |
| WR | Michael Pittman | Ind | 7.70 | 11.07 | 177.20 | 47 Receiving, 6 Rec |
| TE | Travis Kelce | KC | 10.90 | 13.76 | 206.40 | - 1 Rush, 25 Receiving, 5 Rec, 1 TD |
| HB | Rashaad Penny | Sea | 31.50 | 10.41 | 93.70 | 170 Rush, 15 Receiving, 2 Rec, 2 TD |
| PK | Michael Badgley | Ind | 10.00 | 8.00 | 96.00 | 2 FG(40-49), 2 XP |
| DL | Zach Allen | Ari | 3.00 | 4.60 | 69.00 | 1 Tackle, 1 Assist, 1 PD |
| DL | Dre'Mont Jones | Den | 0.00 | 3.93 | 59.00 | Played, No Stats |
| DL | D.J. Wonnum | Min | 2.00 | 4.50 | 72.00 | 2 Tackles |
| LB | T.J. Edwards | Phi | 13.00 | 9.13 | 146.00 | 7 Tackles, 6 Assists |
| LB | Shaquille Leonard | Ind | 16.00 | 11.53 | 173.00 | 6 Tackles, 1 Assist, 1 Int, 1 FF, 1 PD |
| LB | Bobby Okereke | Ind | 11.00 | 9.31 | 149.00 | 10 Tackles, 1 Assist |
| CB | Trevon Diggs | Dal | 3.00 | 8.75 | 140.00 | 3 Tackles |
| S | Kyle Dugger | NE | 8.00 | 8.40 | 126.00 | 1 Tackle, 1 Assist, 1 Int, 1 PD |
| Pos. | 1st Backup | Proteam | TW | PPG | Total | Breakdown |
| QB | Jalen Hurts | Phi | 0(12.96) | 23.06 | 345.96 | 214 Pass, 44 Rush |
| RB | Jaret Patterson | Was | 0(18.30) | 2.90 | 46.40 | 57 Rush, 41 Receiving, 5 Rec, 1 TD |
| WR | A.J. Green | Ari | 0(8.90) | 8.37 | 125.50 | 74 Receiving, 3 Rec |
| TE | Pat Freiermuth | Pit | 0(4.70) | 7.63 | 114.40 | 22 Receiving, 5 Rec |
| RB | Rex Burkhead | Hou | 0(10.90) | 5.58 | 83.70 | 47 Rush, 32 Receiving, 6 Rec |
| PK | Brandon McManus | Den | 0(10.00) | 7.63 | 122.00 | 1 FG(<40), 1 FG(60+), 1 XP |
| LB | Kamu Grugier-Hill | Hou | 0(7.00) | 9.92 | 129.00 | 5 Tackles, 2 Assists |
| Pos. | 2nd Backup | Proteam | TW | PPG | Total | Breakdown |
| QB | Davis Mills | Hou | 0(10.92) | 13.06 | 156.72 | 163 Pass, 4 Rush, 1 TD, 1 Int |
| RB | D'Onta Foreman | Ten | 0(19.20) | 5.43 | 81.50 | 132 Rush, 1 TD |
| WR | DeVante Parker | Mia | 0(6.60) | 9.03 | 81.30 | 46 Receiving, 4 Rec |
| Offense = 126.50 Defense = 56 Total = 182.50 | ||||||
| Pos. | Bench | Proteam | TW | PPG | Total | Breakdown |
| RB | Khalil Herbert | Chi | 0.90 | 4.43 | 70.80 | 9 Rush |
| RB | Miles Sanders | Phi | DNP | 8.77 | 105.20 | Did Not Play |
| RB | Trey Sermon | SF | DNP | 2.98 | 26.80 | Did Not Play |
| RB | Rhamondre Stevenson | NE | 22.70 | 9.52 | 104.70 | 107 Rush, 2 TD |
| RB | Jamaal Williams | Det | 11.90 | 8.43 | 101.10 | 22 Rush, 22 Receiving, 3 Rec, 1 TD |
| WR | Terrace Marshall Jr. | Car | 2.60 | 1.87 | 24.30 | 16 Receiving, 2 Rec |