| Pos. | Starters | Proteam | TW | PPG | Total | Breakdown |
| QB | C.J. Stroud | Hou | 3.64 | 22.00 | 286.04 | 91 Pass |
| RB | Jerome Ford | Cle | 10.70 | 11.15 | 145.00 | 51 Rush, 31 Receiving, 5 Rec |
| RB | Bijan Robinson | Atl | 17.30 | 13.15 | 171.00 | 34 Rush, 54 Receiving, 5 Rec, 1 TD |
| WR | Jameson Williams | Det | 0.40 | 5.14 | 46.30 | 4 Rush |
| WR | DeAndre Hopkins | Ten | 21.90 | 11.94 | 155.20 | 124 Receiving, 7 Rec, 1 TD |
| WR | Tyler Lockett | Sea | 11.90 | 9.97 | 129.60 | 89 Receiving, 6 Rec |
| TE | Cole Kmet | Chi | 9.10 | 8.88 | 115.50 | 66 Receiving, 5 Rec |
| HB | George Pickens | Pit | 4.40 | 9.28 | 120.70 | 19 Receiving, 5 Rec |
| PK | Harrison Butker | KC | 5.00 | 8.46 | 110.00 | 1 FG(<40), 2 XP |
| DL | Harrison Phillips | Min | 8.00 | 6.31 | 82.00 | 3 Tackles, 1 Assist, 1.0 Sack |
| DL | Shaquil Barrett | TB | 4.00 | 6.23 | 81.00 | 2 Tackles, 2 Assists |
| DL | Preston Smith | GB | 1.00 | 5.38 | 70.00 | 1 Assist |
| LB | Eric Kendricks | LAC | 9.00 | 8.64 | 95.00 | 3 Tackles, 2 Assists, 1.0 Sack |
| LB | Devin Lloyd | Jac | 14.00 | 10.27 | 113.00 | 4 Tackles, 7 Assists, 1 Fum Rcvy |
| LB | David Long | Mia | 8.00 | 7.23 | 94.00 | 5 Tackles, 3 Assists |
| CB | Devon Witherspoon | Sea | 1.00 | 8.92 | 107.00 | 1 PD |
| S | Jessie Bates | Atl | 10.00 | 11.54 | 150.00 | 7 Tackles, 2 Assists, 1 PD |
| Pos. | 1st Backup | Proteam | TW | PPG | Total | Breakdown |
| QB | Brock Purdy | SF | 0(25.42) | 23.22 | 301.92 | 368 Pass, 7 Rush, 2 TD, 1 Int |
| RB | D'Onta Foreman | Chi | 0(8.20) | 10.79 | 86.30 | 50 Rush, 22 Receiving, 2 Rec |
| TE | Gerald Everett | LAC | 0(6.40) | 5.88 | 64.70 | 39 Receiving, 5 Rec |
| RB | Ty Chandler | Min | 0(5.70) | 3.22 | 41.80 | 35 Rush, 7 Receiving, 3 Rec |
| DL | Leonard Floyd | Buf | 0(1.00) | 5.23 | 68.00 | 1 Tackle |
| LB | Jahlani Tavai | NE | 0(14.00) | 7.69 | 100.00 | 8 Tackles, 6 Assists |
| CB | Bradley Roby | Phi | 0(7.00) | 5.00 | 20.00 | 5 Tackles, 2 Assists |
| S | Jordan Whitehead | NYJ | 0(3.00) | 8.08 | 105.00 | 1 Tackle, 2 Assists |
| Pos. | 2nd Backup | Proteam | TW | PPG | Total | Breakdown |
| S | Justin Simmons | Den | 0(14.00) | 7.82 | 86.00 | 3 Tackles, 3 Assists, 1.0 Sack, 1 FF, 1 PD |
| Offense = 84.34 Defense = 55 Total = 139.34 | ||||||
| Pos. | Bench | Proteam | TW | PPG | Total | Breakdown |
| QB | Derek Carr | NO | 14.76 | 14.01 | 182.10 | 119 Pass, 2 TD, 1 Int |
| RB | Nick Chubb | Cle | DNP | 10.55 | 21.10 | Did Not Play |
| RB | Justice Hill | Bal | 1.70 | 5.25 | 63.00 | 12 Receiving, 1 Rec |
| TE | Zach Ertz | Ari | DNP | 5.46 | 38.20 | Team had a Bye |
| DL | David Onyemata | Atl | DNP | 6.18 | 68.00 | Did Not Play |
| LB | Jordan Hicks | Min | DNP | 11.50 | 115.00 | Did Not Play |
| LB | Jack Campbell | Det | 10.00 | 5.77 | 75.00 | 6 Tackles, 4 Assists |
| Pos. | Injured List | Proteam | TW | PPG | Total | Breakdown |
| QB | Aaron Rodgers | NYJ | DNP | 0.00 | 0.00 | Did Not Play |