| Pos. | Starters | Proteam | TW | PPG | Total | Breakdown |
| QB | Jake Browning | Cin | 22.96 | 13.18 | 105.42 | 324 Pass, 2 TD, 1 Int |
| RB | Aaron Jones | GB | 8.90 | 9.60 | 76.80 | 53 Rush, 16 Receiving, 4 Rec |
| RB | Tony Pollard | Dal | 6.70 | 12.16 | 170.30 | 52 Rush, 5 Receiving, 2 Rec |
| WR | Cooper Kupp | LAR | 21.10 | 11.63 | 116.30 | 111 Receiving, 8 Rec, 1 TD |
| WR | Michael Pittman | Ind | 9.80 | 12.84 | 179.70 | 78 Receiving, 4 Rec |
| WR | Amon-Ra St. Brown | Det | 20.70 | 15.91 | 206.80 | 112 Receiving, 7 Rec, 1 TD |
| TE | Evan Engram | Jac | 4.80 | 9.58 | 134.10 | 28 Receiving, 4 Rec |
| HB | Zay Flowers | Bal | 1.20 | 9.44 | 132.10 | 7 Receiving, 1 Rec |
| PK | Brandon Aubrey | Dal | 4.00 | 10.64 | 149.00 | 1 FG(<40), 1 XP |
| DL | Carl Granderson | NO | 7.00 | 7.36 | 103.00 | 2 Tackles, 1 Assist, 1.0 Sack |
| DL | Sam Hubbard | Cin | 3.00 | 6.17 | 74.00 | 3 Tackles |
| DL | Haason Reddick | Phi | 2.00 | 0.00 | 0.00 | |
| LB | Tremaine Edmunds | Chi | 21.00 | 11.08 | 133.00 | 5 Tackles, 4 Assists, 1 Int, 1 TD, 1 PD |
| LB | Alex Singleton | Den | 5.00 | 11.29 | 158.00 | 3 Tackles, 2 Assists |
| LB | Robert Spillane | LV | 7.00 | 11.29 | 158.00 | 1 Tackle, 3 Assists, 1 FF |
| CB | Trent McDuffie | KC | 1.00 | 7.29 | 102.00 | 1 Tackle |
| S | Reed Blankenship | Phi | 6.00 | 0.00 | 0.00 | |
| Pos. | 1st Backup | Proteam | TW | PPG | Total | Breakdown |
| QB | Justin Fields | Chi | 0(11.64) | 20.38 | 203.84 | 166 Pass, 30 Rush, 1 TD, 2 Int |
| RB | Kenneth Walker | Sea | 0(18.70) | 0.00 | 0.00 | |
| WR | Rashee Rice | KC | 0(19.60) | 10.72 | 150.10 | 91 Receiving, 9 Rec, 1 TD |
| TE | Cade Otton | TB | 0(5.40) | 6.20 | 86.80 | 44 Receiving, 2 Rec |
| WR | Elijah Moore | Cle | 0(2.70) | 6.22 | 87.10 | 17 Receiving, 2 Rec |
| DL | Kobie Turner | LAR | 0(1.00) | 5.14 | 72.00 | 1 Assist |
| LB | Elandon Roberts | Pit | 0(9.00) | 7.57 | 106.00 | 8 Tackles, 1 Assist |
| S | P.J. Locke | Den | 0(5.00) | 6.78 | 61.00 | 3 Tackles, 1 Assist, 1 PD |
| Offense = 100.16 Defense = 52 Total = 152.16 | ||||||
| Pos. | Bench | Proteam | TW | PPG | Total | Breakdown |
| QB | Jared Goff | Det | 41.12 | 21.44 | 300.18 | 278 Pass, 5 TD |
| QB | Will Levis | Ten | 14.46 | 15.30 | 122.38 | 199 Pass, 25 Rush, 1 TD, 1 Int |
| RB | Josh Jacobs | LV | DNP | 12.58 | 163.60 | Did Not Play |
| RB | Alexander Mattison | Min | DNP | 8.68 | 112.90 | Did Not Play |
| RB | Patrick Taylor | GB | 1.20 | 2.60 | 10.40 | 6 Rush, -4 Receiving, 2 Rec |
| WR | Noah Brown | Hou | 18.20 | 9.81 | 78.50 | 82 Receiving, 8 Rec, 1 TD |
| WR | Zay Jones | Jac | 8.40 | 6.68 | 53.40 | 59 Receiving, 5 Rec |
| LB | Samson Ebukam | Ind | 9.00 | 6.71 | 94.00 | 2 Tackles, 1 Assist, 1.5 Sacks |