| Pos. | Starters | Proteam | TW | PPG | Total | Breakdown |
| QB | Josh Allen | Buf | DNP | 29.52 | 442.76 | Did Not Play |
| RB | Alvin Kamara | NO | 8.60 | 12.56 | 175.80 | 74 Rush, 7 Receiving, 1 Rec |
| RB | David Montgomery | Chi | 4.60 | 10.71 | 160.60 | 24 Rush, 12 Receiving, 2 Rec |
| WR | Chris Godwin | TB | 17.50 | 11.81 | 165.30 | 120 Receiving, 9 Rec, 1 2-Pt, 1 Fumb |
| WR | Jerry Jeudy | Den | 7.30 | 10.64 | 148.90 | 38 Receiving, 7 Rec |
| WR | Tyler Lockett | Sea | 2.50 | 12.26 | 183.90 | 15 Receiving, 2 Rec |
| TE | Travis Kelce | KC | 7.80 | 15.97 | 255.50 | 43 Receiving, 7 Rec |
| HB | Travis Etienne | Jac | 21.50 | 11.51 | 184.20 | 108 Rush, 32 Receiving, 3 Rec, 1 TD |
| PK | Brett Maher | Dal | 10.00 | 10.00 | 160.00 | 1 FG(<40), 1 FG(40-49), 3 XP |
| DL | Demarcus Lawrence | Dal | 10.00 | 6.81 | 109.00 | 3 Tackles, 2 Assists, 1 FF, 2 PD |
| DL | Da'Ron Payne | Was | 13.00 | 7.38 | 118.00 | 3 Tackles, 2 Assists, 2.0 Sacks |
| DL | Kayvon Thibodeaux | NYG | 10.00 | 6.21 | 87.00 | 4 Tackles, 1 Assist, 1.0 Sack, 1 PD |
| LB | Lavonte David | TB | 8.00 | 8.94 | 143.00 | 6 Tackles, 2 Assists |
| LB | Josey Jewell | Den | 8.00 | 12.83 | 154.00 | 4 Tackles, 3 Assists, 1 PD |
| LB | Drue Tranquill | LAC | 9.00 | 10.75 | 172.00 | 6 Tackles, 3 Assists |
| CB | Marlon Humphrey | Bal | 0.00 | 7.06 | 113.00 | Played, No Stats |
| S | Jalen Thompson | Ari | 10.00 | 7.38 | 118.00 | 8 Tackles, 2 Assists |
| Pos. | 1st Backup | Proteam | TW | PPG | Total | Breakdown |
| QB | Sam Darnold | Car | 29.64 | 16.90 | 101.40 | 341 Pass, 20 Rush, 3 TD, 1 Int, 2 Fumb |
| RB | Jamaal Williams | Det | 0(22.20) | 12.67 | 202.70 | 144 Rush, 13 Receiving, 1 Rec, 1 TD |
| WR | Diontae Johnson | Pit | 0(4.50) | 8.18 | 130.90 | 35 Receiving, 2 Rec |
| TE | Hayden Hurst | Cin | DNP | 6.33 | 76.00 | Did Not Play |
| WR | JuJu Smith-Schuster | KC | 0(3.10) | 9.59 | 143.80 | 21 Receiving, 2 Rec |
| DL | Cam Sample | Cin | DNP | 2.00 | 30.00 | Did Not Play |
| LB | Willie Gay | KC | 0(7.00) | 9.42 | 113.00 | 5 Tackles, 2 Assists |
| CB | Rasul Douglas | GB | 0(6.00) | 7.44 | 119.00 | 3 Tackles, 1 Assist, 2 PD |
| S | Derwin James | LAC | DNP | 11.15 | 145.00 | Did Not Play |
| Pos. | 2nd Backup | Proteam | TW | PPG | Total | Breakdown |
| RB | Gus Edwards | Bal | 0(0.20) | 7.34 | 58.70 | 2 Rush |
| WR | Chris Olave | NO | 0(6.20) | 10.76 | 150.70 | 42 Receiving, 4 Rec |
| WR | Richie James | NYG | 0(17.10) | 6.69 | 107.00 | 76 Receiving, 7 Rec, 1 TD |
| DL | Montez Sweat | Was | 0(8.00) | 4.88 | 78.00 | 3 Tackles, 1 Assist, 1.0 Sack |
| Offense = 109.44 Defense = 68 Total = 177.44 | ||||||
| Pos. | Bench | Proteam | TW | PPG | Total | Breakdown |
| QB | Matthew Stafford | LAR | DNP | 14.60 | 131.38 | Did Not Play |
| WR | Greg Dortch | Ari | 3.50 | 5.44 | 81.60 | 15 Receiving, 4 Rec |
| WR | Kadarius Toney | KC | 8.10 | 4.86 | 38.90 | 71 Receiving, 4 Rec, 1 Fumb |
| Pos. | Injured List | Proteam | TW | PPG | Total | Breakdown |
| RB | Rashaad Penny | Sea | DNP | 10.04 | 50.20 | Did Not Play |