| Pos. | Starters | Proteam | TW | PPG | Total | Breakdown |
| QB | Anthony Richardson | Ind | DNP | 19.92 | 79.68 | Did Not Play |
| RB | Kenneth Walker | Sea | 7.40 | 12.41 | 136.50 | 21 Rush, 33 Receiving, 4 Rec |
| RB | De'Von Achane | Mia | 9.60 | 18.94 | 132.60 | 47 Rush, 24 Receiving, 5 Rec |
| WR | Ja'Marr Chase | Cin | 4.40 | 14.99 | 194.82 | 29 Receiving, 3 Rec |
| WR | Courtland Sutton | Den | 13.70 | 11.80 | 153.40 | 62 Receiving, 3 Rec, 1 TD |
| WR | Deebo Samuel | SF | 30.50 | 15.14 | 166.50 | 1 Rush, 149 Receiving, 7 Rec, 2 TD |
| TE | Pat Freiermuth | Pit | 5.30 | 6.09 | 48.70 | 18 Receiving, 3 Rec, 1 2-Pt |
| HB | Jakobi Meyers | LV | 5.00 | 11.17 | 134.00 | 25 Receiving, 5 Rec |
| PK | Nicholas Folk | Ten | 8.00 | 8.54 | 111.00 | 2 FG(<40), 2 XP |
| DL | Bradley Chubb | Mia | 9.00 | 7.46 | 97.00 | 2 Tackles, 3 Assists, 1 Fum Rcvy, 1 PD |
| DL | T.J. Watt | Pit | 5.00 | 11.08 | 144.00 | 3 Tackles, 2 Assists |
| DL | Cameron Jordan | NO | 2.00 | 3.92 | 51.00 | 2 Tackles |
| LB | Germaine Pratt | Cin | 12.00 | 9.62 | 125.00 | 4 Tackles, 6 Assists, 0.5 Sack |
| LB | Patrick Queen | Bal | 6.00 | 9.77 | 127.00 | 3 Tackles, 3 Assists |
| LB | Devin Lloyd | Jac | 14.00 | 10.27 | 113.00 | 4 Tackles, 7 Assists, 1 Fum Rcvy |
| S | Jalen Pitre | Hou | 8.00 | 6.27 | 69.00 | 7 Tackles, 1 Assist |
| Pos. | 1st Backup | Proteam | TW | PPG | Total | Breakdown |
| QB | Jimmy Garoppolo | LV | DNP | 11.16 | 78.10 | Did Not Play |
| RB | Isiah Pacheco | KC | DNP | 13.11 | 157.30 | Did Not Play |
| WR | Skyy Moore | KC | 0 | 3.32 | 43.20 | Played, No Stats |
| TE | Luke Musgrave | GB | DNP | 5.66 | 56.60 | Did Not Play |
| Pos. | 2nd Backup | Proteam | TW | PPG | Total | Breakdown |
| QB | Kenny Pickett | Pit | DNP | 10.18 | 122.20 | Did Not Play |
| WR | Diontae Johnson | Pit | 0(13.20) | 8.40 | 84.00 | 57 Receiving, 3 Rec, 1 TD |
| Offense = 83.90 Defense = 56 Total = 139.90 | ||||||
| Pos. | Bench | Proteam | TW | PPG | Total | Breakdown |
| RB | Leonard Fournette | Buf | DNP | 0.00 | 0.00 | Did Not Play |
| RB | Zamir White | LV | 0.80 | 0.93 | 11.20 | 8 Rush |
| WR | Jerry Jeudy | Den | 2.60 | 6.47 | 77.70 | 16 Receiving, 2 Rec |
| DL | Leonard Floyd | Buf | 1.00 | 5.23 | 68.00 | 1 Tackle |
| DL | Demarcus Lawrence | Dal | 1.00 | 3.92 | 51.00 | 1 Assist |
| DL | Jerry Hughes | Hou | 0.00 | 2.25 | 27.00 | Played, No Stats |
| DL | Von Miller | Buf | 0.00 | 0.50 | 2.00 | Played, No Stats |
| DL | Trey Hendrickson | Cin | 11.00 | 7.46 | 97.00 | 2 Tackles, 2.0 Sacks, 1 PD |
| DL | Uchenna Nwosu | Sea | DNP | 5.00 | 30.00 | Did Not Play |
| LB | Cody Barton | Was | DNP | 8.78 | 79.00 | Team had a Bye |
| LB | Shaq Thompson | Car | DNP | 4.00 | 8.00 | Did Not Play |