| Pos. | Starters | Proteam | TW | PPG | Total | Breakdown |
| QB | Lamar Jackson | Bal | 20.54 | 22.31 | 312.30 | 171 Pass, 97 Rush, 1 TD, 1 Int |
| RB | Joe Mixon | Cin | 13.60 | 13.72 | 192.10 | 47 Rush, 14 Receiving, 3 Rec, 1 TD |
| RB | Alexander Mattison | Min | DNP | 8.68 | 112.90 | Did Not Play |
| WR | Tee Higgins | Cin | 20.10 | 9.17 | 91.70 | 61 Receiving, 4 Rec, 2 TD |
| WR | Michael Pittman | Ind | 9.80 | 12.84 | 179.70 | 78 Receiving, 4 Rec |
| WR | Justin Jefferson | Min | 11.90 | 15.39 | 107.70 | 84 Receiving, 7 Rec |
| TE | Taysom Hill | NO | 1.00 | 8.41 | 109.38 | 1 Rush, 4 Receiving, 1 Rec |
| HB | Dontayvion Wicks | GB | 12.70 | 5.40 | 70.26 | 97 Receiving, 6 Rec |
| PK | Jason Sanders | Mia | 12.00 | 8.14 | 114.00 | 3 FG(<40), 3 XP |
| DL | Alex Highsmith | Pit | 4.00 | 6.86 | 96.00 | 4 Tackles |
| DL | Sam Hubbard | Cin | 3.00 | 6.17 | 74.00 | 3 Tackles |
| DL | Quinnen Williams | NYJ | 5.00 | 5.93 | 83.00 | 2 Tackles, 1 Assist, 0.5 Sack |
| LB | Patrick Queen | Bal | 7.00 | 9.57 | 134.00 | 3 Tackles, 1 Assist, 1 Fum Rcvy |
| LB | Lavonte David | TB | 12.00 | 10.58 | 127.00 | 7 Tackles, 2 Assists, 0.5 Sack, 1 PD |
| LB | Eric Kendricks | LAC | 17.00 | 9.33 | 112.00 | 9 Tackles, 3 Assists, 1.0 Sack, 1 PD |
| CB | Derek Stingley | Hou | 5.00 | 6.56 | 59.00 | 1 Tackle, 2 Assists, 2 PD |
| S | Kevin Byard | Phi | 5.00 | 0.00 | 0.00 | |
| Pos. | 1st Backup | Proteam | TW | PPG | Total | Breakdown |
| QB | Aidan O'Connell | LV | 0(33.92) | 12.95 | 103.62 | 248 Pass, 4 TD |
| RB | Royce Freeman | LAR | 1.60 | 4.86 | 43.70 | 16 Rush |
| WR | Khalil Shakir | Buf | 0 | 4.80 | 67.20 | Played, No Stats |
| TE | Pat Freiermuth | Pit | 0(3.10) | 5.76 | 51.80 | 16 Receiving, 3 Rec |
| WR | Noah Brown | Hou | 0(18.20) | 9.81 | 78.50 | 82 Receiving, 8 Rec, 1 TD |
| PK | Younghoe Koo | Atl | 0(1.00) | 7.71 | 108.00 | 1 XP |
| DL | Zach Sieler | Mia | 0(10.00) | 6.93 | 97.00 | 1 Tackle, 1 Assist, 1.0 Sack, 1 Fum Rcvy, 1 PD |
| LB | David Long | Mia | 0(6.00) | 7.14 | 100.00 | 1 Tackle, 5 Assists |
| CB | Darious Williams | Jac | 0(4.00) | 6.79 | 95.00 | 3 Tackles, 1 Assist |
| S | Jessie Bates | Atl | 0(10.00) | 11.43 | 160.00 | 6 Tackles, 4 Assists |
| Pos. | 2nd Backup | Proteam | TW | PPG | Total | Breakdown |
| QB | Geno Smith | Sea | 0 | 0.00 | 0.00 | |
| RB | Samaje Perine | Den | 0(5.30) | 6.09 | 85.30 | 37 Rush, 11 Receiving, 1 Rec |
| TE | Michael Mayer | LV | 0(11.90) | 4.14 | 57.90 | 39 Receiving, 4 Rec, 1 TD |
| RB | Dalvin Cook | NYJ | 0(1.50) | 2.48 | 34.70 | 4 Rush, 6 Receiving, 1 Rec |
| Offense = 103.24 Defense = 58 Total = 161.24 | ||||||
| Pos. | Bench | Proteam | TW | PPG | Total | Breakdown |
| RB | Ty Montgomery | F/A | DNP | 0.57 | 7.40 | Did Not Play |
| RB | Israel Abanikanda | NYJ | 2.90 | 1.63 | 4.90 | 8 Rush, 11 Receiving, 2 Rec |