| Position | Starters | Proteam | TW | PPG | Total | Breakdown |
|---|---|---|---|---|---|---|
| QB | Matthew Stafford | LAR | 19.46 | 25.88 | 362.28 | 244 Pass, - 3 Rush, 2 TD, 1 Int |
| RB | Joe Mixon | Cin | 6.5 | 16.24 | 227.30 | 58 Rush, 2 Receiving, 1 Rec |
| RB | Miles Sanders | Phi | 15.6 | 9.08 | 99.90 | 131 Rush, 15 Receiving, 2 Rec |
| WR | Keenan Allen | LAC | 16.8 | 13.75 | 178.70 | 78 Receiving, 6 Rec, 1 TD |
| WR | Amari Cooper | Dal | 1.8 | 10.90 | 130.80 | 8 Receiving, 2 Rec |
| WR | Van Jefferson | LAR | 4.3 | 9.26 | 129.70 | 10 Rush, 23 Receiving, 2 Rec |
| TE | Dawson Knox | Buf | 5.8 | 10.39 | 124.70 | 38 Receiving, 4 Rec |
| HB (RB) | Darrell Henderson | LAR | 3.7 | 13.38 | 147.20 | 23 Rush, 4 Receiving, 2 Rec |
| PK | Greg Joseph | Min | 5.0 | 9.00 | 126.00 | 1 FG(<40), 2 XP |
| DL | John Franklin-Myers | NYJ | 1.0 | 4.64 | 65.00 | 1 Assist |
| DL | Yannick Ngakoue | LV | 0.0 | 5.00 | 70.00 | Played, No Stats |
| DL | Montez Sweat | Was | 10.0 | 5.10 | 51.00 | 1 Tackle, 2 Assists, 1.0 Sack, 1 FF |
| LB | Jordan Hicks | Ari | 5.0 | 9.93 | 139.00 | 3 Tackles, 1 Assist, 1 PD |
| LB | Darius Leonard | Ind | 19.0 | 11.21 | 157.00 | 8 Tackles, 2 Assists, 1 Int, 1 FF, 1 PD |
| LB | Foyesade Oluokun | Atl | 10.0 | 12.14 | 170.00 | 7 Tackles, 3 Assists |
| CB | Xavien Howard | Mia | 3.0 | 7.00 | 91.00 | 2 Tackles, 1 Assist |
| S | Antoine Winfield | TB | DNP | 9.18 | 101.00 | Did Not Play |
| Position | 1st Backups | Proteam | TW | PPG | Total | Breakdown |
| QB | Ryan Tannehill | Ten | 0(10.92) | 17.50 | 245.02 | 153 Pass, 18 Rush, 1 TD, 1 Int, 1 Fumb |
| RB | Jamaal Williams | Det | DNP | 8.15 | 81.50 | Did Not Play |
| WR | Jalen Guyton | LAC | 0(8.0) | 5.10 | 71.40 | 10 Receiving, 2 Rec, 1 TD |
| TE | Mike Gesicki | Mia | 0(6.8) | 8.18 | 114.50 | 43 Receiving, 5 Rec |
| HB (WR) | Christian Kirk | Ari | 0(19.9) | 10.32 | 144.52 | 94 Receiving, 9 Rec, 1 TD |
| PK | Chris Boswell | Pit | 0(15.0) | 9.14 | 128.00 | 2 FG(<40), 2 FG(40-49), 1 XP |
| DL | Larry Ogunjobi | Cin | 0(10.0) | 5.21 | 73.00 | 1 Tackle, 3 Assists, 1.5 Sacks |
| LB | Alex Singleton | Phi | 0(11.0) | 9.21 | 129.00 | 4 Tackles, 4 Assists, 1 FF |
| CB | JC Jackson | NE | 0(6.0) | 7.79 | 109.00 | 3 Assists, 3 PD |
| S | Micah Hyde | Buf | 7.0 | 7.43 | 104.00 | 4 Tackles, 2 Assists, 1 PD |
| Position | 2nd Backups | Proteam | TW | PPG | Total | Breakdown |
| RB | Craig Reynolds | Det | 0(12.2) | 1.65 | 23.10 | 112 Rush, 5 Receiving, 1 Rec |
| WR | Emmanuel Sanders | Buf | DNP | 8.28 | 107.70 | Did Not Play |
| HB (WR) | Antoine Wesley | Ari | 0(3.4) | 1.34 | 18.70 | 19 Receiving, 3 Rec |
| DL | David Onyemata | NO | 0(10.0) | 5.83 | 35.00 | 2 Tackles, 4 Assists, 1.0 Sack |
| LB | Isaiah Simmons | Ari | 0(6.0) | 8.07 | 113.00 | 6 Tackles |
| Offense = 78.96 Defense = 55 Total = 133.96 | ||||||
| Position | Bench | Proteam | TW | PPG | Total | Breakdown |
| RB | Samaje Perine | Cin | 0(5.3) | 5.09 | 66.20 | 30 Rush, 13 Receiving, 2 Rec |
| Position | Injured Reserve | Proteam | TW | PPG | Total | Breakdown |
| WR | Will Fuller | Mia | DNP | 1.53 | 4.60 | Did Not Play |