| Round | Overall | Player |
|---|---|---|
| 1 | 7th | RB Joseph Addai Ind |
| 2 | 18th | RB Adrian Peterson Min |
| 3 | 31st | WR Roy Williams Det |
| 4 | 42nd | QB Marc Bulger StL |
| 5 | 55th | RB Brandon Jackson GB |
| 6 | 66th | LB Shawne Merriman SD |
| 7 | 79th | TE Vernon Davis SF |
| 8 | 90th | S Adrian Wilson Ari |
| 9 | 103rd | LB Demarcus Ware Dal |
| 10 | 114th | DL Leonard Little StL |
| 11 | 127th | WR Jerricho Cotchery NYJ |
| 12 | 138th | LB Patrick Willis SF |
| 13 | 151st | WR James Jones GB |
| 14 | 162nd | WR Anthony Gonzalez Ind |
| 15 | 175th | DL Dwight Freeney Ind |
| 16 | 186th | QB Jeff Garcia TB |
| 17 | 199th | PK Jeff Wilkins StL |
| 18 | 210th | CB Rashean Mathis Jac |
| 19 | 223rd | TE Daniel Graham Den |
| 20 | 234th | S Dawan Landry Bal |
| 21 | 247th | LB Julian Peterson Sea |
| 22 | 258th | QB Brady Quinn Cle |
| 23 | 271st | RB Chris Henry Ten |
| 24 | 282nd | CB DeAngelo Hall Atl |
| 25 | 295th | DL Jamaal Anderson Atl |
| 26 | 306th | WR Steve Smith NYG |
| 27 | 319th | RB Najeh Davenport Pit |
| 28 | 330th | PK Rian Lindell Buf |