| Round | Overall | Player |
|---|---|---|
| 1 | 1st | RB LaDainian Tomlinson SD |
| 2 | 24th | QB Carson Palmer Cin |
| 3 | 25th | WR Reggie Wayne Ind |
| 4 | 48th | WR Calvin Johnson Det |
| 5 | 49th | RB Julius Jones Dal |
| 6 | 72nd | S Adrian Wilson Ari |
| 7 | 73rd | RB Jerious Norwood Atl |
| 8 | 96th | TE Kellen Winslow Jr. Cle |
| 9 | 97th | WR Anthony Gonzalez Ind |
| 10 | 120th | DL Will Smith NO |
| 11 | 121st | DL Charles Grant NO |
| 12 | 144th | LB Kirk Morrison Oak |
| 13 | 145th | RB Selvin Young Den |
| 14 | 168th | LB Adalius Thomas NE |
| 15 | 169th | WR James Jones GB |
| 16 | 192nd | QB Chad Pennington NYJ |
| 17 | 193rd | LB Nick Barnett GB |
| 18 | 216th | CB Walt Harris SF |
| 19 | 217th | DL Aaron Smith Pit |
| 20 | 240th | TE Eric Johnson NO |
| 21 | 241st | PK Jason Hanson Det |
| 22 | 264th | PK John Kasay Car |
| 23 | 265th | CB Lito Sheppard Phi |
| 24 | 288th | S Darren Sharper Min |
| 25 | 289th | RB Pierre Thomas Jr. NO |
| 26 | 312th | TE Daniel Graham Den |
| 27 | 313th | QB Trent Green F/A |
| 28 | 336th | WR Reggie Williams Jac |