| Round | Overall | Player |
|---|---|---|
| 1 | 1st | RB LaDainian Tomlinson SD |
| 2 | 24th | RB Laurence Maroney NE |
| 3 | 25th | QB Ben Roethlisberger Pit |
| 4 | 48th | RB Edgerrin James Ari |
| 5 | 49th | TE Antonio Gates SD |
| 6 | 72nd | WR Lee Evans Buf |
| 7 | 73rd | WR Chris Chambers SD |
| 8 | 96th | LB Demarcus Ware Dal |
| 9 | 97th | WR Hines Ward Pit |
| 10 | 120th | RB Ahman Green Hou |
| 11 | 121st | RB Chris Brown Hou |
| 12 | 144th | LB Erin Henderson Min |
| 13 | 145th | DL Elvis Dumervil Den |
| 14 | 168th | LB Lance Briggs Chi |
| 15 | 169th | WR Sidney Rice Min |
| 16 | 192nd | QB Jason Campbell Was |
| 17 | 193rd | S Bernard Pollard KC |
| 18 | 216th | PK Rob Bironas Ten |
| 19 | 217th | DL Darnell Dockett Ari |
| 20 | 240th | S Troy Polamalu Pit |
| 21 | 241st | TE Ben Utecht Cin |
| 22 | 264th | WR David Patten NO |
| 23 | 265th | LB Thomas Howard Oak |
| 24 | 288th | DL Dewayne White Det |
| 25 | 289th | S Antoine Bethea Ind |
| 26 | 312th | CB Leodis McKelvin Buf |
| 27 | 313th | DL Jamaal Anderson Atl |
| 28 | 336th | WR Andre Davis Hou |