| Round | Overall | Player |
|---|---|---|
| 1 | 2nd | RB Adrian Peterson Min |
| 2 | 23rd | RB Maurice Jones-Drew Jac |
| 3 | 26th | WR T.J. Houshmandzadeh Cin |
| 4 | 47th | WR Santonio Holmes Pit |
| 5 | 50th | WR Calvin Johnson Det |
| 6 | 71st | RB Jonathan Stewart Car |
| 7 | 74th | QB Matt Hasselbeck Sea |
| 8 | 95th | LB London Fletcher Was |
| 9 | 98th | RB Chester Taylor Min |
| 10 | 119th | QB Philip Rivers SD |
| 11 | 122nd | LB Paul Posluszny Buf |
| 12 | 143rd | S Sean Jones Cle |
| 13 | 146th | LB Barrett Ruud TB |
| 14 | 167th | DL Tamba Hali KC |
| 15 | 170th | TE Todd Heap Bal |
| 16 | 191st | PK Mason Crosby GB |
| 17 | 194th | QB Matt Leinart Ari |
| 18 | 215th | QB Kurt Warner Ari |
| 19 | 218th | TE Alge Crumpler Ten |
| 20 | 239th | CB Adam Jones Dal |
| 21 | 242nd | WR Reggie Williams Jac |
| 22 | 263rd | TE L.J. Smith Phi |
| 23 | 266th | DL John Abraham Atl |
| 24 | 287th | CB Leigh Bodden Det |
| 25 | 290th | LB Shawne Merriman SD |
| 26 | 311th | DL Antwan Odom Cin |
| 27 | 314th | RB Tatum Bell Den |
| 28 | 335th | WR Steve Smith NYG |