| Round | Overall | Player |
|---|---|---|
| 1 | 11th | RB Laurence Maroney NE |
| 2 | 14th | RB Reggie Bush NO |
| 3 | 35th | RB Willis McGahee Bal |
| 4 | 38th | RB Jonathan Stewart Car |
| 5 | 59th | RB LenDale White Ten |
| 6 | 62nd | RB Julius Jones Sea |
| 7 | 83rd | RB Chris Johnson Ten |
| 8 | 86th | QB Philip Rivers SD |
| 9 | 107th | QB JaMarcus Russell Oak |
| 10 | 110th | QB David Garrard Jac |
| 11 | 131st | QB Brady Quinn Cle |
| 12 | 134th | QB Matt Ryan Atl |
| 13 | 155th | LB Shawne Merriman SD |
| 14 | 158th | LB Julian Peterson Sea |
| 15 | 179th | WR Kevin Curtis Phi |
| 16 | 182nd | WR Robert Meachem NO |
| 17 | 203rd | WR Donte Stallworth Cle |
| 18 | 206th | CB Antonio Cromartie SD |
| 19 | 227th | TE Ben Utecht Cin |
| 20 | 230th | DL Dwight Freeney Ind |
| 21 | 251st | LB LaMarr Woodley Pit |
| 22 | 254th | S Reggie Nelson Jac |
| 23 | 275th | DL Albert Haynesworth Ten |
| 24 | 278th | RB Pierre Thomas Jr. NO |
| 25 | 299th | WR Chad Jackson NE |
| 26 | 302nd | TE John Carlson Sea |
| 27 | 323rd | PK Brandon Coutu Sea |
| 28 | 326th | S Yeremiah Bell Mia |