| Round | Overall | Player |
|---|---|---|
| 1 | 3rd | RB Steven Jackson StL |
| 2 | 22nd | QB Tony Romo Dal |
| 3 | 27th | WR Andre Johnson Hou |
| 4 | 46th | WR Santonio Holmes Pit |
| 5 | 51st | RB Matt Forte Chi |
| 6 | 70th | WR Dwayne Bowe KC |
| 7 | 75th | DL Mario Williams Hou |
| 8 | 94th | LB Jon Beason Car |
| 9 | 99th | RB Chris Perry Cin |
| 10 | 118th | DL Patrick Kerney Sea |
| 11 | 123rd | RB Maurice Morris Sea |
| 12 | 142nd | S Sean Jones Cle |
| 13 | 147th | LB Lofa Tatupu Sea |
| 14 | 166th | RB Justin Fargas Oak |
| 15 | 171st | QB Trent Edwards Buf |
| 16 | 190th | WR Bobby Engram Sea |
| 17 | 195th | LB A.J. Hawk GB |
| 18 | 214th | DL Derrick Harvey Jac |
| 19 | 219th | CB Darrelle Revis NYJ |
| 20 | 238th | TE Tony Scheffler Den |
| 21 | 243rd | LB Barrett Ruud TB |
| 22 | 262nd | WR Justin Gage Ten |
| 23 | 267th | RB Kenny Watson Cin |
| 24 | 286th | DL Antwan Odom Cin |
| 25 | 291st | TE Marcedes Lewis Jac |
| 26 | 310th | WR Kevin Walter Hou |
| 27 | 315th | LB Jordon Dizon Det |
| 28 | 334th | S Kenny Phillips NYG |