| Round | Overall | Player |
|---|---|---|
| 1 | 3rd | RB Steven Jackson StL |
| 2 | 22nd | WR Brandon Marshall Den |
| 3 | 27th | RB Laurence Maroney NE |
| 4 | 46th | RB Kevin Smith Det |
| 5 | 51st | WR Wesley Welker NE |
| 6 | 70th | QB Jay Cutler Den |
| 7 | 75th | QB Marc Bulger StL |
| 8 | 94th | TE Vernon Davis SF |
| 9 | 99th | WR DeSean Jackson Phi |
| 10 | 118th | WR Eddie Royal Den |
| 11 | 123rd | LB D.J. Williams Den |
| 12 | 142nd | CB Richard Marshall Car |
| 13 | 147th | LB Jerod Mayo NE |
| 14 | 166th | WR Chris Henry Cin |
| 15 | 171st | WR James Hardy Buf |
| 16 | 190th | DL Chris Long StL |
| 17 | 195th | S Troy Polamalu Pit |
| 18 | 214th | DL Dwight Freeney Ind |
| 19 | 219th | DL Matt Roth Mia |
| 20 | 238th | RB Jason Wright Cle |
| 21 | 243rd | S Sammy Knight NYG |
| 22 | 262nd | LB Mike Peterson Jac |
| 23 | 267th | LB Julian Peterson Sea |
| 24 | 286th | DL Jevon Kearse Ten |
| 25 | 291st | PK Matt Prater Den |
| 26 | 310th | TE Donald Lee GB |
| 27 | 315th | S Lawyer Milloy Atl |
| 28 | 334th | CB Brandon Flowers KC |