| Round | Overall | Player |
|---|---|---|
| 1 | 4th | RB Joseph Addai Ind |
| 2 | 21st | WR Marques Colston NO |
| 3 | 28th | RB Reggie Bush NO |
| 4 | 45th | TE Kellen Winslow Jr. Cle |
| 5 | 52nd | QB Jay Cutler Den |
| 6 | 69th | LB DeMeco Ryans Hou |
| 7 | 76th | WR Dwayne Bowe KC |
| 8 | 93rd | LB Paul Posluszny Buf |
| 9 | 100th | QB Philip Rivers SD |
| 10 | 117th | RB Brandon Jackson GB |
| 11 | 124th | WR Anthony Gonzalez Ind |
| 12 | 141st | DL Elvis Dumervil Den |
| 13 | 148th | DL Derrick Burgess Oak |
| 14 | 165th | RB Dominic Rhodes Ind |
| 15 | 172nd | DL Gaines Adams TB |
| 16 | 189th | CB Darrelle Revis NYJ |
| 17 | 196th | QB Jason Campbell Was |
| 18 | 213th | RB Kevin Jones Chi |
| 19 | 220th | LB A.J. Hawk GB |
| 20 | 237th | PK Adam Vinatieri Ind |
| 21 | 244th | S Chinedum Ndukwe Cin |
| 22 | 261st | RB Tatum Bell Den |
| 23 | 268th | RB Warrick Dunn TB |
| 24 | 285th | S Madieu Williams Min |
| 25 | 292nd | RB Carnell Williams TB |
| 26 | 309th | WR Ernest Wilford Mia |
| 27 | 316th | CB Adam Jones Dal |
| 28 | 333rd | LB Jordon Dizon Det |