| Round | Overall | Player |
|---|---|---|
| 1 | 4th | RB DeAngelo Williams Car |
| 2 | 21st | RB Kevin Smith Det |
| 3 | 28th | WR Roddy White Atl |
| 4 | 45th | WR Vincent Jackson SD |
| 5 | 52nd | QB Matt Schaub Hou |
| 6 | 69th | WR Bernard Berrian Min |
| 7 | 76th | TE Chris Cooley Was |
| 8 | 93rd | LB D'Qwell Jackson Cle |
| 9 | 100th | RB LeSean McCoy Phi |
| 10 | 117th | WR Josh Morgan SF |
| 11 | 124th | LB LaMarr Woodley Pit |
| 12 | 141st | S Gibril Wilson Cin |
| 13 | 148th | QB David Garrard Jac |
| 14 | 165th | CB Chris Gamble Car |
| 15 | 172nd | RB Peyton Hillis Cle |
| 16 | 189th | RB Le'Ron McClain Bal |
| 17 | 196th | CB Quentin Jammer SD |
| 18 | 213th | S Michael Griffin Ten |
| 19 | 220th | WR Steve Smith NYG |
| 20 | 237th | PK Josh Brown StL |
| 21 | 244th | LB Brian Orakpo Was |
| 22 | 261st | DL Kevin Williams Min |
| 23 | 268th | WR Nate Burleson Det |
| 24 | 285th | DL Cullen Jenkins GB |
| 25 | 292nd | TE Chris Baker NE |
| 26 | 309th | PK Ryan Succop KC |
| 27 | 316th | RB BenJarvus Green-Ellis NE |
| 28 | 333rd | DL Derrick Harvey Jac |