| Round | Overall | Player |
|---|---|---|
| 1 | 7th | QB Drew Brees NO |
| 2 | 18th | WR Calvin Johnson Det |
| 3 | 31st | RB Ronnie Brown Mia |
| 4 | 42nd | RB Pierre Thomas Jr. NO |
| 5 | 55th | WR Roy Williams Dal |
| 6 | 66th | RB Thomas Jones KC |
| 7 | 79th | WR Lee Evans Buf |
| 8 | 90th | RB Donald Brown Ind |
| 9 | 103rd | WR Santana Moss Was |
| 10 | 114th | WR Percy Harvin Min |
| 11 | 127th | DL Osi Umenyiora NYG |
| 12 | 138th | DL Darryl Tapp Phi |
| 13 | 151st | LB Ernie Sims Phi |
| 14 | 162nd | RB Jamal Lewis Cle |
| 15 | 175th | LB Channing Crowder Mia |
| 16 | 186th | S Kevin Payne StL |
| 17 | 199th | CB Cortland Finnegan Ten |
| 18 | 210th | TE Brent Celek Phi |
| 19 | 223rd | WR Muhsin Muhammad Car |
| 20 | 234th | RB Shonn Greene NYJ |
| 21 | 247th | TE Tony Scheffler Det |
| 22 | 258th | QB Marc Bulger Bal |
| 23 | 271st | LB Gary Brackett Ind |
| 24 | 282nd | DL Shaun Ellis NYJ |
| 25 | 295th | PK John Kasay Car |
| 26 | 306th | TE Anthony Fasano Mia |
| 27 | 319th | S Sean Jones TB |
| 28 | 330th | WR Miles Austin Dal |