| Round | Overall | Player |
|---|---|---|
| 1 | 6th | RB Steven Jackson StL |
| 2 | 19th | WR Greg Jennings GB |
| 3 | 30th | WR Marques Colston NO |
| 4 | 43rd | QB Donovan McNabb Was |
| 5 | 54th | RB Marshawn Lynch Buf |
| 6 | 67th | LB Patrick Willis SF |
| 7 | 78th | DL Mario Williams Hou |
| 8 | 91st | DL Julius Peppers Chi |
| 9 | 102nd | TE John Carlson Sea |
| 10 | 115th | WR Lance Moore NO |
| 11 | 126th | RB Fred Jackson Buf |
| 12 | 139th | CB Charles Tillman Chi |
| 13 | 150th | LB Erin Henderson Min |
| 14 | 163rd | RB Michael Bush Oak |
| 15 | 174th | TE Kellen Winslow Jr. TB |
| 16 | 187th | S Brandon Meriweather NE |
| 17 | 198th | QB Jason Campbell Oak |
| 18 | 211th | WR Nate Washington Ten |
| 19 | 222nd | RB Willis McGahee Bal |
| 20 | 235th | LB James Laurinaitis StL |
| 21 | 246th | WR Chaz Schilens Oak |
| 22 | 259th | DL Tamba Hali KC |
| 23 | 270th | PK Nicholas Folk NYJ |
| 24 | 283rd | S Bob Sanders Ind |
| 25 | 294th | WR Michael Crabtree SF |
| 26 | 307th | RB Samkon Gado Mia |
| 27 | 318th | WR Isaac Bruce SF |
| 28 | 331st | QB Michael Vick Phi |