| Round | Overall | Player |
|---|---|---|
| 1 | 4th | RB DeAngelo Williams Car |
| 2 | 21st | WR Greg Jennings GB |
| 3 | 28th | WR Anquan Boldin Bal |
| 4 | 45th | QB Philip Rivers SD |
| 5 | 52nd | TE Dallas Clark Ind |
| 6 | 69th | RB Derrick Ward TB |
| 7 | 76th | RB Felix Jones Dal |
| 8 | 93rd | DL Julius Peppers Chi |
| 9 | 100th | RB Jonathan Stewart Car |
| 10 | 117th | WR Lance Moore NO |
| 11 | 124th | LB Bradie James Dal |
| 12 | 141st | QB Joe Flacco Bal |
| 13 | 148th | DL Tamba Hali KC |
| 14 | 165th | RB Earnest Graham TB |
| 15 | 172nd | QB Matt Cassel KC |
| 16 | 189th | S Jarrad Page KC |
| 17 | 196th | WR Kenny Britt Ten |
| 18 | 213th | LB Julian Peterson Det |
| 19 | 220th | RB Tashard Choice Dal |
| 20 | 237th | LB Stephen Cooper SD |
| 21 | 244th | CB Quentin Jammer SD |
| 22 | 261st | PK Ryan Longwell Min |
| 23 | 268th | WR Isaac Bruce SF |
| 24 | 285th | WR Darrius Heyward-Bey Oak |
| 25 | 292nd | DL Richard Seymour Oak |
| 26 | 309th | RB Carnell Williams TB |
| 27 | 316th | WR Michael Crabtree SF |
| 28 | 333rd | WR Mark Clayton Bal |