| Round | Overall | Player |
|---|---|---|
| 1 | 1st | RB Adrian Peterson Min |
| 2 | 24th | WR Vincent Jackson TB |
| 3 | 25th | QB Philip Rivers SD |
| 4 | 48th | DL Justin Tuck NYG |
| 5 | 49th | RB Jahvid Best Det |
| 6 | 72nd | DL Trent Cole Phi |
| 7 | 73rd | TE Vernon Davis SF |
| 8 | 96th | WR Julio Jones Atl |
| 9 | 97th | LB Derrick Johnson KC |
| 10 | 120th | WR Pierre Garcon Was |
| 11 | 121st | CB Charles Woodson GB |
| 12 | 144th | LB Desmond Bishop GB |
| 13 | 145th | WR Robert Meachem NO |
| 14 | 168th | QB Donovan McNabb F/A |
| 15 | 169th | RB C.J. Spiller Buf |
| 16 | 192nd | TE Jared Cook Ten |
| 17 | 193rd | RB Derrick Ward Hou |
| 18 | 216th | WR Jacoby Ford Oak |
| 19 | 217th | S George Wilson Buf |
| 20 | 240th | QB Colt McCoy Cle |
| 21 | 241st | RB Roy Helu Was |
| 22 | 264th | CB DeAngelo Hall Was |
| 23 | 265th | RB Jason Snelling Atl |
| 24 | 288th | S Dawan Landry Jac |
| 25 | 289th | WR Harry Douglas Atl |
| 26 | 312th | RB Toby Gerhart Min |
| 27 | 313th | PK Rob Bironas Ten |
| 28 | 336th | LB Thomas Davis Car |