| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Samuel Basallo | C | Bal | 21 | |
| Carson Kelly | C | ChN | 31 | |
| Shea Langeliers | C | Oak | 27 | |
| Triston Casas | 1B | Bos | 25 | May 03, 2025:60 Day IL |
| Deyvison De Los Santos | 1B | Mia | 22 | |
| Vinnie Pasquantino | 1B | KC | 27 | |
| Carlos Correa | SS (3B) | Hou | 30 | |
| Marcelo Mayer | SS (2B,3B) | Bos | 22 | July 25, 2025:60 Day IL |
| Ryan Ritter | SS (2B) | Col | 24 | |
| Trea Turner | SS | Phi | 32 | September 08, 2025:10 Day IL |
| JJ Wetherholt | SS | StL | 23 | |
| Alex Bregman | 3B | Bos | 31 | |
| Kyle Karros | 3B | Col | 23 | |
| Sal Stewart | 3B (1B) | Cin | 21 | |
| Dylan Beavers | OF | Bal | N/A | |
| Carson Benge | OF | NYN | 22 | |
| Nathan Church | OF | StL | 25 | |
| Adolis Garcia | OF | Tex | 32 | |
| Michael Harris II | OF | Atl | 24 | |
| Austin Hays | OF | Cin | 30 | |
| Josh Lowe | OF | TB | 27 | |
| Mickey Moniak | OF | Col | 27 | |
| Tyler O'Neill | OF | Bal | 30 | |
| James Wood | OF | Was | 22 | |
| Lucas Giolito | SP | Bos | 31 | |
| Dean Kremer | SP | Bal | 29 | |
| Bryce Miller | SP | Sea | 27 | |
| Cole Ragans | SP | KC | 27 | June 11, 2025:60 Day IL |
| Chris Sale | SP | Atl | 36 | |
| Jameson Taillon | SP | ChN | 33 | |
| Hurston Waldrep | SP | Atl | N/A | |
| Ryne Nelson | RP (SP) | Ari | 27 | |
| Emilio Pagan | RP | Cin | 34 | |
| Daniel Palencia | RP | ChN | N/A | September 08, 2025:15 Day IL |