| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Dillon Dingler | C | Det | N/A | |
| Sean Murphy | C | Atl | 30 | |
| Bo Naylor | C | Cle | 25 | |
| Adley Rutschman | C | Bal | 27 | June 21, 2025:10 Day IL |
| Carlos Santana | 1B | Cle | 39 | |
| Christian Walker | 1B | Hou | 34 | |
| Jose Altuve | 2B (OF) | Hou | 35 | |
| Brice Turang | 2B | Mil | 25 | |
| J.P. Crawford | SS | Sea | 30 | |
| Corey Seager | SS | Tex | 31 | |
| Masyn Winn | SS | StL | 23 | |
| Alex Bregman | 3B | Bos | 31 | May 24, 2025:10 Day IL |
| Maikel Garcia | 3B (2B,SS,OF) | KC | 25 | |
| Yoan Moncada | 3B | LAA | 30 | June 02, 2025:10 Day IL |
| Jorge Polanco | 3B (2B) | Sea | 31 | |
| Eugenio Suarez | 3B | Ari | 33 | |
| Wilyer Abreu | OF | Bos | 26 | |
| Ian Happ | OF | ChN | 30 | |
| Teoscar Hernández | OF | LAD | 32 | |
| Trevor Larnach | OF | Min | 28 | |
| Jorge Soler | OF | LAA | 32 | June 20, 2025:10 Day IL |
| Kyle Stowers | OF | Mia | 27 | |
| Christian Yelich | OF | Mil | 33 | |
| Pat Corbin | SP | Tex | 35 | |
| Nathan Eovaldi | SP | Tex | 35 | |
| Lucas Giolito | SP | Bos | 30 | |
| Shota Imanaga | SP | ChN | 31 | |
| Merrill Kelly | SP | Ari | 36 | |
| Yusei Kikuchi | SP | LAA | 34 | |
| Brady Singer | SP | Cin | 28 | |
| Ranger Suarez | SP | Phi | 29 | |
| Pete Fairbanks | RP | TB | 31 | |
| Ryan Helsley | RP | StL | 30 | |
| Kenley Jansen | RP | LAA | 37 |