| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| J.T. Realmuto | C | Phi | 34 | |
| Keibert Ruiz | C | Was | 26 | June 24, 2025:10 Day IL |
| Gary Sanchez | C | Bal | 32 | |
| Jonathan Aranda | 1B | TB | 27 | |
| Willson Contreras | 1B | StL | 33 | |
| Ozzie Albies | 2B | Atl | 28 | |
| Max Muncy | SS (2B,3B) | Oak | 22 | |
| Jeremy Pena | SS | Hou | 27 | June 30, 2025:15 Day IL-Rib |
| Trea Turner | SS | Phi | 32 | |
| Josh Jung | 3B | Tex | 27 | |
| Max Muncy | 3B | LAD | 34 | |
| Matt Shaw | 3B | ChN | 23 | |
| Jo Adell | OF | LAA | 26 | |
| Alec Burleson | OF (1B) | StL | 26 | |
| Corbin Carroll | OF | Ari | 24 | June 24, 2025:10 Day IL |
| Trent Grisham | OF | NYA | 28 | |
| Jake Meyers | OF | Hou | 29 | |
| Lars Nootbaar | OF | StL | 27 | |
| Luis Robert Jr. | OF | ChA | 27 | June 29, 2025:10 Day IL |
| Jesus Sanchez | OF | Mia | 27 | |
| Pavin Smith | OF (1B) | Ari | 29 | |
| Mike Trout | OF | LAA | 33 | |
| Shane Baz | SP | TB | 26 | |
| Erick Fedde | SP | StL | 32 | |
| Kevin Gausman | SP | Tor | 34 | |
| Matthew Liberatore | SP | StL | 25 | |
| Chris Paddack | SP | Min | 29 | |
| Quinn Priester | SP (RP) | Mil | 24 | |
| Chris Sale | SP | Atl | 36 | June 21, 2025:15 Day IL |
| Max Scherzer | SP | Tor | 40 | |
| Spencer Schwellenbach | SP | Atl | 25 | |
| Kodai Senga | SP | NYN | 32 | June 13, 2025:15 Day IL |
| Ranger Suarez | SP | Phi | 29 | |
| Bryan Woo | SP | Sea | 25 |