| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Jonah Heim | C | Tex | 30 | |
| Cal Raleigh | C | Sea | 28 | |
| Rhys Hoskins | 1B | Mil | 32 | |
| Ryan O'Hearn | 1B (OF) | SD | 32 | |
| Zach McKinstry | 2B (SS,3B,OF) | Det | 30 | |
| Jeff McNeil | 2B (OF) | NYN | 33 | |
| Gleyber Torres | 2B | Det | 28 | |
| J.P. Crawford | SS | Sea | 30 | |
| Francisco Lindor | SS | NYN | 31 | |
| Manny Machado | 3B | SD | 33 | |
| Ryan McMahon | 3B | NYA | 30 | |
| Alec Burleson | OF (1B) | StL | 26 | |
| Oneil Cruz | OF | Pit | 27 | |
| Ian Happ | OF | ChN | 31 | |
| Trevor Larnach | OF | Min | 28 | |
| Brandon Nimmo | OF | NYN | 32 | |
| Jurickson Profar | OF | Atl | 32 | |
| Anthony Santander | OF | Tor | 31 | |
| Gavin Sheets | OF (1B) | SD | 29 | |
| Chandler Simpson | OF | TB | 24 | |
| Chris Bassitt | SP | Tor | 36 | September 20, 2025:15 Day IL |
| Bailey Falter | SP | KC | 28 | August 23, 2025:15 Day IL |
| Max Fried | SP | NYA | 31 | |
| Bryce Miller | SP | Sea | 27 | |
| David Peterson | SP | NYN | 30 | |
| Carlos Rodon | SP | NYA | 32 | |
| Max Scherzer | SP | Tor | 41 | |
| Ranger Suarez | SP | Phi | 30 | |
| Logan Webb | SP | SF | 28 | |
| Kyle Finnegan | RP | Det | 34 | |
| Tanner Scott | RP | LAD | 31 | |
| Ryan Walker | RP | SF | N/A |