| Round | Overall | Player |
|---|---|---|
| 1 | 5th | OF Grady Sizemore Cle |
| 2 | 20th | 1B Prince Fielder Mil |
| 3 | 29th | 2B Brian Roberts Bal |
| 4 | 44th | 1B Joey Votto Cin |
| 5 | 53rd | SP Josh Beckett Bos |
| 6 | 68th | C Ryan Doumit Pit |
| 7 | 77th | OF Chris Young Ari |
| 8 | 92nd | SS Troy Tulowitzki Col |
| 9 | 101st | 3B Edwin Encarnacion Tor |
| 10 | 116th | OF Jay Bruce Cin |
| 11 | 125th | SP Matt Cain SF |
| 12 | 140th | RP Carlos Marmol ChN |
| 13 | 149th | SP Clayton Kershaw LAD |
| 14 | 164th | SP Manny Parra Mil |
| 15 | 173rd | SP Jered Weaver LAA |
| 16 | 188th | OF Adam Jones Bal |
| 17 | 197th | SP Paul Maholm Pit |
| 18 | 212th | RP Jason Motte StL |
| 19 | 221st | 1B Conor Jackson Ari |
| 20 | 236th | SP Anibal Sanchez Fla |
| 21 | 245th | DH Jack Cust Oak |
| 22 | 260th | 3B Chone Figgins Sea |
| 23 | 269th | SP Ben Sheets Oak |
| 24 | 284th | C Ramon Hernandez Cin |
| 25 | 293rd | DH Nick Johnson NYA |
| 26 | 308th | 2B Chris Getz KC |
| 27 | 317th | SS Jack Wilson Sea |
| 28 | 332nd | SP Kelvim Escobar LAA |
| 29 | 341st | OF Cody Ross Fla |