| Round | Overall | Player |
|---|---|---|
| 1 | 8th | 3B Alex Rodriguez NYA |
| 2 | 17th | 1B Miguel Cabrera Det |
| 3 | 32nd | 2B Brandon Phillips Cin |
| 4 | 41st | 1B Joey Votto Cin |
| 5 | 56th | OF Carlos Lee Hou |
| 6 | 65th | OF Nelson Cruz Tex |
| 7 | 80th | SP Cole Hamels Phi |
| 8 | 89th | OF Manny Ramirez ChA |
| 9 | 104th | 2B Howie Kendrick LAA |
| 10 | 113th | SP Ubaldo Jimenez Col |
| 11 | 128th | SS Stephen Drew Ari |
| 12 | 137th | SP Scott Baker Min |
| 13 | 152nd | OF Michael Bourn Hou |
| 14 | 161st | OF Ryan Ludwick SD |
| 15 | 176th | RP Frank Francisco Tex |
| 16 | 185th | SP Jonathan Sanchez SF |
| 17 | 200th | OF Corey Hart Mil |
| 18 | 209th | SP Jason Frasor Tor |
| 19 | 224th | 1B Chris Davis Tex |
| 20 | 233rd | 1B Adam LaRoche Was |
| 21 | 248th | SP Francisco Liriano Min |
| 22 | 257th | C Yadier Molina StL |
| 23 | 272nd | SP Ted Lilly LAD |
| 24 | 281st | RP Matt Capps Min |
| 25 | 296th | OF Conor Jackson Oak |
| 26 | 305th | SP Joba Chamberlain NYA |
| 27 | 320th | SP Hiroki Kuroda LAD |
| 28 | 329th | C Kelly Shoppach TB |
| 29 | 344th | SP Matt Thornton ChA |