| Round | Overall | Player |
|---|---|---|
| 1 | 6th | OF Ryan Braun Mil |
| 2 | 19th | 3B David Wright NYN |
| 3 | 30th | OF Jacoby Ellsbury Bos |
| 4 | 43rd | 1B Kendrys Morales LAA |
| 5 | 54th | OF Ichiro Suzuki Sea |
| 6 | 67th | SP Jon Lester Bos |
| 7 | 78th | 2B Ben Zobrist TB |
| 8 | 91st | RP Joakim Soria KC |
| 9 | 102nd | SP Javier Vazquez Fla |
| 10 | 115th | OF Denard Span Min |
| 11 | 126th | SP Wandy Rodriguez Hou |
| 12 | 139th | OF Chris Coghlan Fla |
| 13 | 150th | SP Carlos Zambrano ChN |
| 14 | 163rd | C Miguel Montero Ari |
| 15 | 174th | RP Carlos Marmol ChN |
| 16 | 187th | 3B Jorge Cantu Tex |
| 17 | 198th | SP Rick Porcello Det |
| 18 | 211th | OF Alexis Rios ChA |
| 19 | 222nd | SP Jorge de la Rosa Col |
| 20 | 235th | DH Nick Johnson NYA |
| 21 | 246th | 1B Jeff Clement Pit |
| 22 | 259th | C Miguel Olivo Sea |
| 23 | 270th | SS Jack Wilson Sea |
| 24 | 283rd | DH Travis Hafner Cle |
| 25 | 294th | SP Gil Meche KC |
| 26 | 307th | 2B Freddy Sanchez SF |
| 27 | 318th | 2B Brendan Ryan Sea |
| 28 | 331st | SP Carl Pavano Min |
| 29 | 342nd | OF Nolan Reimold Bal |