| Round | Overall | Player |
|---|---|---|
| 1 | 12th | DH Victor Martinez Det |
| 2 | 13th | SP Zack Greinke Mil |
| 3 | 36th | 1B Derrek Lee Bal |
| 4 | 37th | SP Justin Verlander Det |
| 5 | 60th | OF Curtis Granderson NYA |
| 6 | 61st | 2B Brian Roberts Bal |
| 7 | 84th | 1B Adam Dunn ChA |
| 8 | 85th | RP Jose Valverde Det |
| 9 | 108th | 3B Miguel Tejada SD |
| 10 | 109th | SS Asdrubal Cabrera Cle |
| 11 | 132nd | OF Jay Bruce Cin |
| 12 | 133rd | SP Aaron Harang SD |
| 13 | 156th | OF Mike Cameron Bos |
| 14 | 157th | C A.J. Pierzynski ChA |
| 15 | 180th | RP Brad Lidge Phi |
| 16 | 181st | 3B Brandon Inge Det |
| 17 | 204th | 2B Luis Castillo NYN |
| 18 | 205th | SP Edwin Jackson ChA |
| 19 | 228th | SS J.J. Hardy Bal |
| 20 | 229th | OF Magglio Ordonez Det |
| 21 | 252nd | OF Vernon Wells Tor |
| 22 | 253rd | SP Nick Blackburn Min |
| 23 | 276th | OF Luke Scott Bal |
| 24 | 277th | SP Bronson Arroyo Cin |
| 25 | 300th | OF Drew Stubbs Cin |
| 26 | 301st | RP Fernando Rodney LAA |
| 27 | 324th | 1B Carlos Guillen Det |
| 28 | 325th | SP Jason Marquis Was |
| 29 | 348th | SP Micah Owings Cin |