| Round | Overall | Player |
|---|---|---|
| 1 | 2nd | 1B Albert Pujols StL |
| 2 | 23rd | OF Matt Kemp LAD |
| 3 | 26th | C Brian McCann Atl |
| 4 | 47th | 3B Pablo Sandoval SF |
| 5 | 50th | SS Jose Reyes NYN |
| 6 | 71st | SP Clayton Kershaw LAD |
| 7 | 74th | OF Carlos Quentin ChA |
| 8 | 95th | SP John Lackey Bos |
| 9 | 98th | OF Jason Heyward ATL |
| 10 | 119th | OF Carlos Gonzalez Col |
| 11 | 122nd | SP Rick Porcello Det |
| 12 | 143rd | SP Francisco Liriano Min |
| 13 | 146th | SP Stephen Strasburg Was |
| 14 | 167th | SS Asdrubal Cabrera Cle |
| 15 | 170th | 1B James Loney LAD |
| 16 | 191st | SP Jeff Niemann TB |
| 17 | 194th | C Chris Iannetta Col |
| 18 | 215th | OF Chris Young Ari |
| 19 | 218th | RP Chris Perez Cle |
| 20 | 239th | OF Alex Gordon KC |
| 21 | 242nd | RP Mike Gonzalez Bal |
| 22 | 263rd | RP Matt Lindstrom Col |
| 23 | 266th | 2B Clint Barmes Col |
| 24 | 287th | SP Brad Penny Det |
| 25 | 290th | C Carlos Santana Cle |
| 26 | 311th | 2B Blake Dewitt ChN |
| 27 | 314th | 1B Aubrey Huff SF |
| 28 | 335th | 3B Eric Chavez Oak |
| 29 | 338th | SP Todd Wellemeyer SF |