| Round | Overall | Player |
|---|---|---|
| 1 | 12th | 3B Evan Longoria TB |
| 2 | 13th | 1B Adrian Gonzalez Bos |
| 3 | 36th | 2B Dustin Pedroia Bos |
| 4 | 37th | SP Felix Hernandez Sea |
| 5 | 60th | SP Ubaldo Jimenez Col |
| 6 | 61st | OF Shin-Soo Choo Cle |
| 7 | 84th | RP Francisco Cordero Cin |
| 8 | 85th | OF Hunter Pence Hou |
| 9 | 108th | OF Adam Jones Bal |
| 10 | 109th | RP Rafael Soriano TB |
| 11 | 132nd | SP James Shields TB |
| 12 | 133rd | SP Wandy Rodriguez Hou |
| 13 | 156th | SP Edwin Jackson ChA |
| 14 | 157th | OF Johnny Damon Det |
| 15 | 180th | SS Orlando Cabrera Cin |
| 16 | 181st | SP Joe Blanton Phi |
| 17 | 204th | C A.J. Pierzynski ChA |
| 18 | 205th | SP Ervin Santana LAA |
| 19 | 228th | RP Brad Lidge Phi |
| 20 | 229th | 3B Placido Polanco Phi |
| 21 | 252nd | SP Kevin Correia Pit |
| 22 | 253rd | DH Hideki Matsui Oak |
| 23 | 276th | C Ben Molina Tex |
| 24 | 277th | 1B Lyle Overbay Tor |
| 25 | 300th | SP Michael Pelfrey NYN |
| 26 | 301st | 2B Akinori Iwamura Pit |
| 27 | 324th | SP Brett Myers Hou |
| 28 | 325th | SS Edgar Renteria Cin |
| 29 | 348th | OF Rick Ankiel Atl |