| Round | Overall | Player |
|---|---|---|
| 1 | 4th | 2B Robinson Cano NYA |
| 2 | 21st | SP Tim Lincecum SF |
| 3 | 28th | C Buster Posey SF |
| 4 | 45th | OF Andre Ethier LAD |
| 5 | 52nd | SP Tommy Hanson Atl |
| 6 | 69th | OF Nick Markakis Bal |
| 7 | 76th | DH Billy Butler KC |
| 8 | 93rd | 3B Casey Mcgehee Pit |
| 9 | 100th | SS Starlin Castro ChN |
| 10 | 117th | SP Philip Hughes NYA |
| 11 | 124th | SP John Lackey Bos |
| 12 | 141st | OF Vernon Wells LAA |
| 13 | 148th | SP Ryan Dempster ChN |
| 14 | 165th | SP C.J. Wilson LAA |
| 15 | 172nd | 1B James Loney LAD |
| 16 | 189th | SP Derek Lowe Atl |
| 17 | 196th | OF Bryce Harper Was |
| 18 | 213th | OF Coco Crisp Oak |
| 19 | 220th | 2B Juan Uribe LAD |
| 20 | 237th | 1B Ty Wigginton Col |
| 21 | 244th | 2B Omar Infante Fla |
| 22 | 261st | 1B Daric Barton Oak |
| 23 | 268th | SP Ivan Nova NYA |
| 24 | 285th | SS Asdrubal Cabrera Cle |
| 25 | 292nd | SP Kyle Drabek Tor |
| 26 | 309th | 3B Kevin Kouzmanoff KC |
| 27 | 316th | OF Marlon Byrd ChN |
| 28 | 333rd | C Yorvit Torrealba Tex |
| 29 | 340th | SP Kyle McClellan StL |